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Clinical implementation of PLANET® Dose for dosimetric assessment after [177Lu]Lu-DOTA-TATE: comparison with Dosimetry Toolkit® and OLINDA/EXM® V1.0
(2021)
The aim of this study was to compare a commercial dosimetry workstation (PLANET® Dose) and the dosimetry approach (GE Dosimetry Toolkit® and OLINDA/EXM® V1.0) currently used in our department for quantification of the ...
Dosimetry and Toxicity Studies of the Novel Sulfonamide Derivative of Sulforhodamine 101([18f]srf101) at a Preclinical Level
(2019)
Abstract: Background: The SR101 N-(3-[18F]Fluoropropyl) sulfonamide ([18F]SRF101) is a Sul forhodamine 101 derivative that was previously synthesised by our group. The fluorescent dye SR101 has been reported as a marker ...
Implementation of patient dosimetry in the clinical practice after targeted radiotherapy using [177Lu-[DOTATO,Tyr3]-octreotate
(2018-11-29)
Background: This study’s aim was to develop our dosimetric methodology using a commercial workstation for the
routine evaluation of the organs at risk during peptide receptor radionuclide therapy (PRRT) with 177Lu.
Methods: ...
Comparison of commercial dosimetric software platforms in patients treated with 177Lu-DOTATATE for peptide receptor radionuclide therapy
(2020)
Purpose
The aim of this study was to quantitatively compare five commercial dosimetric software platforms based on the analysis of clinical datasets of patients who benefited from peptide receptor radionuclide therapy ...
Monte Carlo dosimetry of a realistic multicellular model of follicular lymphoma in a context of radioimmunotherapy
(2020)
Purpose
Small-scale dosimetry studies generally consider an artificial environment where the tumors are spherical and the radionuclides are homogeneously biodistributed. However, tumor shapes are irregular and radiopharmaceutical ...
Biological and dosimetric evaluation of [11C]S-adenosyl methionine as a potential agent for prostate cancer diagnosis
(2018)
Introduction: [11C]Choline ([11C]COL) has been widely used for prostate cancer diagnosis; however, this
radiopharmaceutical is not recommended for patients with a low absolute PSA value (< 1 ng/mL) due to its
limited ...
Evaluation of [18F] FNM biodistribution and dosimetry based on whole-body PET imaging of rats
(2018)
Introduction: The aim of this work was to study the biodistribution, metabolism and radiation dosimetry of rats
injected with [18F]FNM using PET/CT images. This novel radiotracer targeting NMDA receptor has potential ...
Modelling SPECT auto-contouring acquisitions for 177Lu & 131I molecular radiotherapy using new developments in Geant4/GATE
(2022)
Purpose
Monte Carlo modelling of SPECT imaging in Molecular Radiotherapy can improve activity quantification. Until now, SPECT modelling with GATE only considered circular orbit (CO) acquisitions. This cannot reproduce ...
OpenDose: Open access resources for nuclear medicine dosimetry
(2020)
Radiopharmaceutical dosimetry depends on the localization in
space and time of radioactive sources and requires the estimation
of the amount of energy emitted by the sources deposited within
targets. In particular, when ...