Listar Biología por autor "362036f2-3a1c-4699-8a95-91c3baedb7d1"
Mostrando ítems 1-3 de 3
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A time- and cost-effective strategy to sequence mammalian Y Chromosomes: an application to the de novo assembly of gorilla Y
Tomaszkiewicz, Marta; Rangavittal, Samarth; Cechova, Monika; Campos Sánchez, Rebeca; Fescemyer, Howard W.; Harris, Robert; Ye, Danling; O'Brien, Patricia C.M.; Chikhi, Rayan; Ryder, Oliver A.; Ferguson Smith, Malcolm A.; Medvedev, Paul; Makova, Kateryna D.; Campos Sánchez, Rebeca (2016-02)The mammalian Y Chromosome sequence, critical for studying male fertility and dispersal, is enriched in repeats and palindromes, and thus, is the most difficult component of the genome to assemble. Previously, expensive ... -
Integration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data Analysis
Campos Sánchez, Rebeca; Cremona, Marzia A.; Pini, Alessia; Chiaromonte, Francesca; Makova, Kateryna D. (2016-06-16)Endogenous retroviruses (ERVs), the remnants of retroviral infections in the germ line, occupy ~8% and ~10% of the human and mouse genomes, respectively, and affect their structure, evolution, and function. Yet we still ... -
Reverse Transcription Errors and RNA-DNA Differences at Short Tandem Repeats
Fungtammasan, Arkarachai; Tomaszkiewicz, Marta; Campos Sánchez, Rebeca; Eckert, Kristin A.; DeGiorgio, Michael; Makova, Kateryna D. (2016-07-12)Transcript variation has important implications for organismal function in health and disease. Most transcriptome studies focus on assessing variation in gene expression levels and isoform representation. Variation at the ...