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Phytochemical characterization of extracts of the mesocarp of Bactris gasipaes and evaluation of its antioxidant power for pharmaceutical dermal formulations 

Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo; Ramírez Arguedas, Nils Antonio; Baltodano Viales, Eleaneth; Blanco Barrantes, Jeimy; Porras Navarro, Marta (2019)
The Bactris gasipaes is a native palm from Central America which its fruit is known as pejibaye, its wood is also used for the manufacture of various utensils, the marrow of its tender stems is edible and it is called ...
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Rubus adenotrichus fruit extracts phytochemical characterization and antioxidant power evaluation for dermocosmetic formulations 

Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo; Ramírez Arguedas, Nils Antonio; Fonseca González, Lidiette; Campos Fernández, Jorge Alberto (2017)
There are more than 700 species of the genus Rubus, popularly known as Mora (tropical highland blackberry). In Costa Rica, the species Rubus adenotrichus has been characterized by its high content of antioxidant substances, ...
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Determination of the Impact Caused by Direct Compression on the Crystalline State of Rupatadine Fumarate 10 mg Tablets 

Castillo Henríquez, Luis; Vargas Zúñiga, Rolando; Madrigal Redondo, German; Carazo Berrocal, Gustavo; Hanley Vargas, Georgia (2019-11-08)
The aim of this study is to determine the impact caused by direct compression on the crystalline state of two prototypes of Rupatadine fumarate 10 mg tablets. The tablets were manufactured through direct compression. ...
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Design of Experiments for the Establishment of the Dissolution Test Conditions of Rupatadine Fumarate 10 mg tablets 

Castillo Henríquez, Luis; Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo (2019)
Design of Experiments (DoE) is a statistical model that aims to determine if the factors under study affect the response, and if so, it determines the conditions under which this variable of interest can be optimized. In ...
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Identification of rupatadine fumarate polymorphic crystalline forms in pharmaceutical raw materials 

Castillo Henríquez, Luis; Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo (2018)
Polymorphism analysis of pharmaceutical raw materials is considered one of the most relevant evaluations that should be done. As we know, different crystal forms from the same molecule have differences in terms of their ...
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Combined use of DSC, TGA, XDR and NIR in the compatibility study of preformulation mixtures for the development of 10 mg tablets of Rupatadine Fumarate 

Castillo Henríquez, Luis; Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo (2018)
It is essential to guarantee physico-chemical compatibility between the active pharmaceutical ingredient (API) and the components that are planned to be used in the development of a pharmaceutical formulation. A successful ...

Innovation in the production of a cream based on thermal waters from the surroundigs of the Arenal Volcano in Costa Rica 

Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo; Ramírez Arguedas, Nils Antonio (2015)
Introduction: Since 2009 the University of Costa Rica, through the Faculty of Pharmacy, is dedicated to promote a model of development in cosmetics in small and medium industries in rural or poorest areas of Costa Rica, ...
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Physicochemical characterization of therapeutic peloids from the surroundings of Costa Rica Arenal Volcano 

Madrigal Redondo, German; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo; Ramírez Arguedas, Nils Antonio (2015)
Costa Rica is a volcanic country, containing a variety of peloids with different physicochemical properties; also its main source of income is the tourism. Most of their abundant natural resources have not been characterized ...
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Identification of solid phase state of hemi-dihydrate atorvastatin in pharmaceutical raw materials 

Madrigal Redondo, German; Carazo Berrocal, Gustavo; Vargas Zúñiga, Rolando; Ramírez Arguedas, Nils Antonio (2015)
Determining the spatial configuration of the structures of compounds used in the production of medicines is extremely important due to the different characteristics of each of them in its solid ...

Development of immediate release Rupatadine fumarate 10 mg tablets: A Quality by Design (QbD) approach 

Castillo Henríquez, Luis; Vargas Zúñiga, Rolando; Carazo Berrocal, Gustavo; Madrigal Redondo, German; Calvo Guzmán, Briner; Baltodano Viales, Eleaneth (2019)
The main objective of this research is to develop an immediate release Rupatadine fumarate 10 mg tablets formulation by direct compression, through a Quality by Design approach in Costa Rica. Methods: According to a ...
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  • Repositorios universitarios

  • Repositorio del SIBDI-UCR
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Repositorio Institucional de la Universidad de Costa Rica. Algunos derechos reservados. Este repositorio funciona con DSpace.