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Phytochemical characterization of extracts of the mesocarp of Bactris gasipaes and evaluation of its antioxidant power for pharmaceutical dermal formulations
(2019)
The Bactris gasipaes is a native palm from Central America which its fruit is known as pejibaye, its
wood is also used for the manufacture of various utensils, the marrow of its tender stems is edible and it
is called ...
Rubus adenotrichus fruit extracts phytochemical characterization and antioxidant power evaluation for dermocosmetic formulations
(2017)
There are more than 700 species of the genus Rubus, popularly known as Mora (tropical
highland blackberry). In Costa Rica, the species Rubus adenotrichus has been characterized
by its high content of antioxidant substances, ...
Determination of the Impact Caused by Direct Compression on the Crystalline State of Rupatadine Fumarate 10 mg Tablets
(2019-11-08)
The aim of this study is to determine the impact caused by direct compression on the crystalline state of two
prototypes of Rupatadine fumarate 10 mg tablets. The tablets were manufactured through direct compression. ...
Design of Experiments for the Establishment of the Dissolution Test Conditions of Rupatadine Fumarate 10 mg tablets
(2019)
Design of Experiments (DoE) is a statistical model that aims to determine if the factors under study affect the response, and if so, it determines
the conditions under which this variable of interest can be optimized. In ...
Identification of rupatadine fumarate polymorphic crystalline forms in pharmaceutical raw materials
(2018)
Polymorphism analysis of pharmaceutical raw materials is considered one of the most relevant
evaluations that should be done. As we know, different crystal forms from the same molecule have
differences in terms of their ...
Combined use of DSC, TGA, XDR and NIR in the compatibility study of preformulation mixtures for the development of 10 mg tablets of Rupatadine Fumarate
(2018)
It is essential to guarantee physico-chemical compatibility between the active pharmaceutical ingredient (API) and the components that are planned to be used in the development of a pharmaceutical formulation. A successful ...
Innovation in the production of a cream based on thermal waters from the surroundigs of the Arenal Volcano in Costa Rica
(2015)
Introduction: Since 2009 the University of Costa Rica, through the
Faculty of Pharmacy, is dedicated to promote a model of development
in cosmetics in small and medium industries in rural or poorest areas of
Costa Rica, ...
Physicochemical characterization of therapeutic peloids from the surroundings of Costa Rica Arenal Volcano
(2015)
Costa Rica is a volcanic country, containing a variety of peloids with different physicochemical properties; also its main
source of income is the tourism. Most of their abundant natural resources have not been characterized ...
Identification of solid phase state of hemi-dihydrate atorvastatin in pharmaceutical raw materials
(2015)
Determining the spatial configuration of the structures of compounds used in the production of medicines is extremely important due to the different characteristics of each of them in its solid ...
Development of immediate release Rupatadine fumarate 10 mg tablets: A Quality by Design (QbD) approach
(2019)
The main objective of this research is to develop an immediate release Rupatadine fumarate 10
mg tablets formulation by direct compression, through a Quality by Design approach in Costa
Rica.
Methods: According to a ...