Now showing items 1-10 of 35
Development of immediate release Rupatadine fumarate 10 mg tablets: A Quality by Design (QbD) approach
The main objective of this research is to develop an immediate release Rupatadine fumarate 10 mg tablets formulation by direct compression, through a Quality by Design approach in Costa Rica. Methods: According to a ...
Implementación de un modelo de gestión de la innovación para empresas artesanales, pequeñas y medianas del sector farmacéutico en Costa Rica
Implementation of a model of management of innovation for artisanal small and medium enterprises of the pharmaceutic al sector in Costa Rica
El objetivo de este artículo es describir los resultados obtenidos de la implementación de un modelo socio-económico que permite gestionar la innovación en empresas artesanales a través de la articulación de sectores ...
Physicochemical and Microbiological Assays for Quality Evaluation of a Brand of Mentha piperita Tisanes in Costa Rica Market: Employment of the Central American Technical Regulation
Mentha piperita is a natural hybrid of water mint (Mentha aquatica) and spearmint (Mentha spicata L.), that are consumed as tisanes. For that reason, the present work evaluated physicochemical and microbiological aspects ...
Combined use of DSC, TGA, XDR and NIR in the compatibility study of preformulation mixtures for the development of 10 mg tablets of Rupatadine Fumarate
It is essential to guarantee physico-chemical compatibility between the active pharmaceutical ingredient (API) and the components that are planned to be used in the development of a pharmaceutical formulation. A successful ...
Furosemide Diuretic Activity Evaluation in Female Sprague-Dawley Rats
This research article focuses on the evaluation of the diuretic activity of Furosemide administered to a group of female Sprague Dawley rats, through the use of metabolic boxes. Methods: A hydration volume of 5 mL/100 g ...
Evaluation of the critical points in the validation of 500 mg levofloxacin tablets for dissolution profile
The method was validated by ultraviolet spectrophotometry for the determination of levofloxacin 500 mg tablets using dissolution profiles to establish therapeutic equivalence. The parameters were satisfactory according ...
Physicochemical Characterization of a Liposomal Formulation Based on Glucosamine and Vitamin D, Commercialized as a Nutritional Supplement
In the last years, the transport and release mechanism of bioactive compounds has been studied. The liposomes are multivesicular systems that enhance the absorption, stability, and transport of these compounds. The ...
Quality control performed on liposomal formulations based on guarana extract, vitamins a, c, e, b1, b2, b5, b6, b12, biotin and folic acid, used as nutritional products
The study of has increased in the last decades. One of the mechanisms that has acquired great relevance is to formulate using liposomal vesicles. Liposomes are structures that enh and transport of active compounds, which ...
Comparison of the antifungal and antibacterial effect of the essential oil and ethanolic extract of the Zingiber officinale Rhizome (Ginger) cultivated in the San Carlos zone, Costa Rica in order to standardize a hydroponic medicinal cultivation of the same
Introduction: Ginger is a medicinal plant native to India. Its potential use in cosmetics, medicines and natural products has been reported, however depending on the conditions of cultivation the medicinal components of ...
Control de calidad de un colirio comercializado en las macrobióticas de Costa Rica que declara contener materias primas naturales
Quality control of an ophthalmic solution commercialized in Costa Rica macrobiotics that claim to contain natural raw materials
Justificación y objetivo: El Reglamento Técnico Centroamericano (RTCA) 11.03.64:11 (Productos Farmacéuticos. Productos Naturales Medicinales para Uso Humano. Registro Sanitario) especifica que los colirios no se pueden ...