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Genetic structure of personality factors and bipolar disorder in families segregating bipolar disorder
(Journal of Affective Disorders xxx (2011) xxx–xxx, 2011)
Bipolar disorder (BPD) has been associated with variations in personality dimensions,
but the nature of this relationship has been unclear. Inthis study, theheritabilities of BPDandtheBig
Five personality factors and the ...
Neurocognitive endophenotypes for bipolar disorder identified in multiplex multigenerational families
(Arch Gen Psychiatry. 2010;67(2):168-177, 2010-02-01)
Context: Although genetic influences on bipolar disorder
are well established, localization of genes that predispose
to the illness has proven difficult. Given that genes
predisposing to bipolar disorder may be transmitted ...
A schizophrenia gene locus on chromosome 17q21 in a new set of families of mexican and central american ancestry: evidence from the NIMH genetics of schizophrenia in latino populations study
(Am J Psychiatry 2009;166:442-449, 2009-02-02)
The present study investigated a new set of families of Latin American ancestry in order to detect the location of genes predisposing to schizophrenia and related psychotic disorders. Method: A genome-wide scan was performed ...
Genetic Structure Analysis of Three Hispanic Populations from Costa Rica, Mexico, and the Southwestern United States Using Y-Chromosome STR Markers and mtDNA Sequences
(Human Biology, October 2006, v. 78, no. 5, pp. 551–563., 2006)
Two hundred seventeen male subjects from Costa Rica, Mexico,
and the Hispanic population of the southwestern United States were
studied. Twelve Y-chromosome STRs and the HVSI sequence of the mtDNA
were analyzed to ...
Adjudicating Neurocognitive Endophenotypes for Schizophrenia
(American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 144B:242–249 (2007), 2007-03-05)
Although genetic influences on schizophrenia
are well established, localization of the genes
responsible for this illness has proven extremely
difficult. Given evidence that genes predisposing
to schizophrenia may be ...
The epsin 4 gene is associated with psychotic disorders in families of Latin American origin
(Schizophrenia Research vol. 106, num 2 (2008) 253–257, 2008-10-20)
This study attempted to replicate evidence for association of the Epsin 4 gene (which encodes
enthoprotin, a protein involved in vesicular transport) to schizophrenia in a new sample of
families segregating schizophrenia ...
Substance use disorder and schizophrenia: prevalence and sociodemographic characteristics in the Latin American population
Esquizofrenia y trastorno en el consumo de sustancias: prevalencia y características sociodemográficas en la población Latina
(Actas Esp Psiquiatr 2011;39(2):123-30, 2011)
El interés por comprender la co-morbilidad de la esquizofrenia
y el trastorno en el uso de sustancias, ha aumentado
debido al incremento de este diagnóstico, a los
efectos negativos observados en el sujeto y a los ...
Resultados de la categorización de una muestra de pacientes con diagnóstico de egreso de esquizofrenia
(Acta Médica Costarricense, abril-junio 2002, vol 44 (2), 2002-04)
La esquizofrenia es una enfermedad que afecta aproximadamente al 1% de la población mundial. Es
una de las enfermedades psiquiátricas más debilitantes con un alto costo económico, social, familiar y personal.
En Costa ...
In vivo and in vitro genetic evidence of involvement of neuregulin 1 in immune system dysregulation
(J Mol Med (Berl). 2010 November ; 88(11): 1133–1141, 2010-11)
Neuregulin 1 (NRG1) has been implicated in several disorders including breast cancer, multiple sclerosis, and schizophrenia. Also, recent evidence suggests that NRG1 may play a role in regulation of inflammation and immune ...
Suggestive evidence for association between L-type voltage-gated calcium channel (CACNA1C) gene haplotypes and bipolar disorder in latinos: a family-based association study
(Bipolar Disorders 2013: 15: 206–214, 2013-02-25)
Objectives: Through recent genome-wide association studies (GWASs),
several groups have reported significant association between variants in
the calcium channel, voltage-dependent, L-type, alpha 1C subunit
(CACNA1C) and ...