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A schizophrenia gene locus on chromosome 17q21 in a new set of families of mexican and central american ancestry: evidence from the NIMH genetics of schizophrenia in latino populations study
(Am J Psychiatry 2009;166:442-449, 2009-02-02)
The present study investigated a new set of families of Latin American ancestry in order to detect the location of genes predisposing to schizophrenia and related psychotic disorders. Method: A genome-wide scan was performed ...
Genetic Structure Analysis of Three Hispanic Populations from Costa Rica, Mexico, and the Southwestern United States Using Y-Chromosome STR Markers and mtDNA Sequences
(Human Biology, October 2006, v. 78, no. 5, pp. 551–563., 2006)
Two hundred seventeen male subjects from Costa Rica, Mexico, and the Hispanic population of the southwestern United States were studied. Twelve Y-chromosome STRs and the HVSI sequence of the mtDNA were analyzed to ...
The epsin 4 gene is associated with psychotic disorders in families of Latin American origin
(Schizophrenia Research vol. 106, num 2 (2008) 253–257, 2008-10-20)
This study attempted to replicate evidence for association of the Epsin 4 gene (which encodes enthoprotin, a protein involved in vesicular transport) to schizophrenia in a new sample of families segregating schizophrenia ...
The serotonin transporter 5-HTTPR polymorphism is associated with current and lifetime depression in persons with chronic psychotic disorders
(Acta Psychiatr Scand 2009: 119: 117–127, 2009-01-11)
Objective: Variation in the serotonin transporter gene (SLC6A4) promoter region has been shown to influence depression in persons who have been exposed to a number of stressful life events. Method: We evaluated whether ...
Diagnosis of Schizophrenia in Latino Populations. A Comparison of Direct Interview and Consensus Based Multi-Source Methods
(Journal of Nervous and Mental Disease 2009;197: 530–535, 2009-07)
We determined the rates of agreement between diagnoses, using the Diagnostic Interview for Genetic Studies (DIGS) and diagnoses arrived at, using additional sources of information, to establish whether there are differences ...