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High mitochondrial mutation rates estimated from deep-rooting Costa Rican pedigrees
(American Journal of Physical Anthropology 2012 July ; 148(3): 327–333., 2012-07)
Estimates of mutation rates for the noncoding hypervariable Region I (HVR-I) of mitochondrial
DNA (mtDNA) vary widely, depending on whether they are inferred from phylogenies (assuming
that molecular evolution is clock-like) ...
Mitochondrial polymorphisms are associated both with increased and decreased longevity
(Hum Hered 2009;67:147–153, 2008-12-15)
Previous work compared frequency of longevity-associated polymorphisms (LAPS) in long-lived individuals and in controls from the general population (primarily in Europe and Japan), suggesting the polymorphisms are responsible ...
Ancestry Informative Markers Clarify the Regional Admixture Variation in the Costa Rican Population
(Human Biology Open Access Pre-Prints. Paper 34., 2013-10-09)
Study for the first time a random sample from all regions of the country with AIMS (Ancestry Informative Markers) to address the individual and regional admixture proportions. A sample of 160 male individuals was screened ...
Genetic Structure Analysis of Three Hispanic Populations from Costa Rica, Mexico, and the Southwestern United States Using Y-Chromosome STR Markers and mtDNA Sequences
(Human Biology, October 2006, v. 78, no. 5, pp. 551–563., 2006)
Two hundred seventeen male subjects from Costa Rica, Mexico,
and the Hispanic population of the southwestern United States were
studied. Twelve Y-chromosome STRs and the HVSI sequence of the mtDNA
were analyzed to ...
A Second Locus for an Axonal Form of Autosomal Recessive Charcot-Marie-Tooth Disease Maps to Chromosome 19q13.3
(American Journal Human Genetic ; 68 (1 p. 269-274, 2001)
Autosomal recessive Charcot-Marie-Tooth disease (CMT) represents a heterogeneous group of disorders affecting the peripheral nervous system. The axonal form of the disease is designated as "CMT type 2" (CMT2), and one locus ...
Phenylketonuria in Costa Rica: preliminary spectrum of PAH mutations and their associations with highly polymorphic haplotypes
(1996)
A preliminary evaluation of the molecular basis of phenylketonuria (PKU) in Costa Rica was made by performing mutational analyses in the six PKU families identified to date. These studies revealed the presence of the ...
Genetic variation and racial admixture in the Miskito of the southern Mosquito Shore, Nicaragua
(1998)
A survey of the electrophoretic variation at eleven loci red-blood cell enzymes. hemoglobins and serum proteins was performed on a sample of 59 Miskitos stemming from the southernmost part of the Mosquito shore of Nicaragua. ...
Migration and Genetic Infrastructure of the Central American Guaymi and Their Affinities With Other Tribal Groups
(American Journal of Phisical Antropology: 58 p.201-214, 1982-06)
New genetic data on 40 red cell enzymes, antigenic blood groups, and serum proteins representing 42 separate loci, are reported for two Guaymi communities in Southeastern Costa Rica. These two settlements, Limoncito and ...
Demografía y genética de la población amerindia Guaymí de Limoncito, Costa Rica
(Revista de Biología Tropical 29(1):123-131, 1981)
El estudio de las poblaciones indígenas es muy importante para la comprensión de la estructura cultural, genética y ecológica de los grupos humanos. En las últimas dos décadas se ha desarrollado un intenso trabajo teórico ...
Estudios evolutivos y biomédicos en dos poblaciones indígenas Guaymies de Costa Rica
(Vínculos 7(1), 1-7. 1981, 1981)
A biomedical study which included genetic, demographic, nutritional and health aspects was
carried out in two amerindian Guayrni populations, Abrojo and Limoncito, located in Southeastern
Costa Rica. Both groups originated ...