• Association of interleukin-1B and interleukin-1RN polymorphisms with gastric cancer in a high-risk population of Costa Rica 

      Alpízar Alpízar, Warner; Pérez Pérez, Guillermo Ignacio; Une, Clas Allan; Cuenca Berger, Patricia; Sierra Ramos, Rafaela (Clinical and Experimental Medicine 5 p.169-176, 2005-09-13)
      Several risk factors have been associated with gastric cancer, among them Helicobacter pylori infection. This bacterium yields inflammation, the degree of which depends on the bacterial strain and the severity of the host ...
    • Helicobater pylori. ¿Es posible la erradicación? 

      Sierra Ramos, Rafaela; Muñoz Calero, Nubia; Sanabria, Marjorie; Mora Zuñiga, Francisco; Quirós, Eber; Brenes Pino, Fernando; Campos Rudín, Manuel; Mora, Walter; Altman Ortiz, Rodrigo (1999)
      Objetivo: Erradicar H. pylori en pacientes dispepticos de una población de alto riesgo de cancer gástrico Poblacion y metodos: A 174 pacientes dispepticos, de una poblacion de alto riesgo de cancer gastric°, se les ...
    • Neutrophil gelatinase-associated lipocalin (NGAL/Lcn2) is upregulated in gastric mucosa infected with Helicobacter pylori 

      Alpízar Alpízar, Warner; Didrik Laerum, Ole; Illemann, Martin; Ramírez Corrales, José Alberto; Arias, Adriana; Malespín Bendaña, Wendy Karina; Ramírez Mayorga, Vanessa; Lund, Leif R.; Borregaard, Niels; Schnack Nielsen, Boye (2009-09)
      Helicobacter pylori infection is one of the most significant risk factors for gastric cancer. The infection is established early in life and persists lifelong leading to a sustained chronic inflammation. Iron is essential ...
    • TAZ Controls Helicobacter pylori-Induced Epithelial–Mesenchymal Transition and Cancer Stem Cell-Like Invasive and Tumorigenic Properties 

      Tiffon, Camille; Giraud, Julie; Molina Castro, Silvia Elena; Peru, Sara; Seeneevassen, Lornella; Sifré, Elodie; Staedel, Cathy; Bessède, Emilie; Dubus, Pierre; Mégraud, Francis; Lethours, Philippe; Martin, Océane C.B.; Varon, Christine (2020)
      Helicobacter pylori infection, the main risk factor for gastric cancer (GC), leads to an epithelial–mesenchymal transition (EMT) of gastric epithelium contributing to gastric cancer stem cell (CSC) emergence. The Hippo ...
    • Virulence factor genotyping of Helicobacter pylori isolated from Costa Rican dyspeptic patients 

      Molina Castro, Silvia Elena; Garita Cambronero, Jerson; Malespín Bendaña, Wendy Karina; Une, Clas Allan; Ramírez Mayorga, Vanessa (2019-01-14)
      Background and aims: Costa Rica is one of the countries with the highest incidence and mortality rates for gastric cancer. Helicobacter pylori infection rates are high in the whole country. We have previously shown that ...