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A review of the genus Rickettsia in Central America 

Bermúdez Castillero, Sergio Eduardo; Troyo Rodríguez, Adriana (2018)
In this paper, we present a historical review of rickettsiosis in Central America and also the most recent findings of Rickettsia in ectoparasites. All countries of Central America have records of rickettsiosis. Regarding ...
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Calcium plays a key role in the effects induced by a snake venom Lys49 phospholipase A2 homologue on a lymphoblastoid cell line 

Mora Rodríguez, Rodrigo Antonio; Maldonado, Alexis; Valverde Rojas, Berta E.; Gutiérrez, José María (2006-01)
A catalytically-inactive Lys49 phospholipase A2 homologue from the venom of the snake Bothrops asper induces diverse effects (necrosis, apoptosis and proliferation) in a lymphoblastoid cell line, depending on the toxin ...

Molecular Detection of Bartonella Species in Fleas Collected from Dogs and Cats from Costa Rica 

Rojas Campos, Norman; Troyo Rodríguez, Adriana; Castillo, Daniela; Gutiérrez, Ricardo; Harrus, Shimon (2015-09)
The bacterial genus Bartonella includes several species with zoonotic potential, some of which are common in domestic dogs and cats, as well as in their fleas. Because there is no previous information about the presence ...

Pathological and biochemical changes induced in mice after intramuscular injection of venom from newborn specimens of the snake Bothrops asper (Terciopelo) 

Chaves Mora, Fernando; Gutiérrez, José María; Brenes Pino, Fernando (1992-09)
Venom from newborn Bothrops asper snakes has higher lethal, hemorrhagic, edema-forming, proteolytic and defibrinating activities than venom from adult B. asper specimens. Electrophoretic analysis confirmed the variation ...
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Antivenoms for the treatment of snakebite envenomings: The road ahead 

Gutiérrez, José María; León Montero, Guillermo; Burnouf, Thierry (2011-05)
The parenteral administration of antivenoms is the cornerstone of snakebite envenoming therapy. Efforts are made to ensure that antivenoms of adequate efficacy and safety are available world-wide. We address the main issues ...

Bioavailability of in-feed tetracyclines is influenced to a greater extent by crude protein rather than calcium 

Granados Chinchilla, Fabio; Rodríguez Sánchez, César (2014-12)
Feed is a common vehicle for tetracycline administration in animal farming. However, veterinarians and farmers often overlook that common feed components, such as proteins and calcium, may interact with these drugs and ...

Amino acid sequence of a myotoxic Lys49-phospholipase A2 homologue from the venom of Cerrophidion (Bothrops) godmani 

de Sousa, Marcelo Valle; Morhy, Lauro; Arni, Raghuvir K.; Ward, Richard John; Díaz Oreiro, Cecilia; Gutiérrez, José María (1998-05-19)
The complete amino acid sequence of myotoxin II (godMT-II), a myotoxic phospholipase A2 (PLA2) homologue from the venom of the Central American crotaline snake Cerrophidion (Bothrops) godmani, was determined by direct ...

Skeletal muscle necrosis and regeneration after injection of Thalassophryne nattereri (niquim) fish venom in mice 

Lopes Ferreira, Mónica; Núñez, Javier; Rucavado Romero, Alexandra; Farsky, Sandra H. P.; Lomonte, Bruno; Angulo Ugalde, Yamileth; Moura Da Silva, Ana M.; Gutiérrez, José María (2001-02)
Stings by Thalassophryne nattereri are responsible for envenomation of fishermen in north-eastern Brazil. Its venom induces prominent local tissue damage, characterized by pain, oedema and necrosis. The pathogenesis of ...
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Bacterias multirresistentes a los antibióticos aisladas de niños hospitalizados de "alto riesgo" 

Peñaranda, María Elena; Brenes, Carmen; Vargas, Guillermo; Mata Jiménez, Leonardo (Revista Médica del Hospital Nacioanl de Niños Dr. Carlos Sáenz, 1978)
Between January and September, 1977, 43 strains of Klebslella-Enterobac-ter, 17 of Pseudomonas and 6 of Escherlchla coli —all resistant to several drugs—were isolated from 66 children hospitalized in the National Children's ...

Phospholipases A2: Unveiling the secrets of a functionally versatile group of snake venom toxins 

Gutiérrez, José María; Lomonte, Bruno (2013-02)
Phospholipases A2 (PLA2s) are abundant components of snake venoms, where they play toxic and digestive roles. Despite having a similar three-dimensional structure, venom PLA2s exert an amazing variety of toxic and ...
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