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Gene Expression Dynamics Induced by Ciprofloxacin and Loss of LexA Function in Pseudomonas aeruginosa PAO1 Using Data Mining and Network Analysis
(2018)
Pseudomonas aeruginosa is an opportunistic
pathogen that causes a variety of infections in humans and
frequently develops mechanisms of resistance to antibiotics, which
makes its treatment difficult. In this study we ...
Population Genomics Insights into Adaptive Evolution and Ecological Differentiation in Streptomycetes
(2019)
Deciphering the genomic variation that represents microevolutionary processes toward species divergence is key to understanding microbial speciation, which has long been under debate. Streptomycetes are filamentous bacteria ...
Avances de la bioinformática en Costa Rica: Vista retrospectiva y perspectivas
Bioinformatics advances in Costa Rica: Retrospective view and perspectives
(2021-11-09)
Introducción: La disciplina científica de la bioinformática tiene el potencial de generar aplicaciones innovadoras para las sociedades humanas. Costa Rica, pequeña en tamaño y población en comparación con otros países de ...
Phylogenetic analyses of antibiotic-producing Streptomyces sp. isolates obtained from the stingless-bee Tetragonisca angustula (Apidae: Meliponini)
(2019)
Many insects have been associated with actinobacteria in protective symbiosis where antimicrobial metabolites inhibit host pathogens. However, the microbiota of neotropical insects such as the stingless-bee Tetragonisca ...
Transcriptomic determinants of the response of ST-111 Pseudomonas aeruginosa AG1 to ciprofloxacin identified by a top-down systems biology approach
(2020)
Pseudomonas aeruginosa is an opportunistic pathogen that thrives in diverse environments and causes a variety of human infections. Pseudomonas aeruginosa AG1 (PaeAG1) is a high-risk sequence type 111 (ST-111) strain isolated ...
DNase activity in Costa Rican crotaline snake venoms: quantification of activity and identification of electrophoretic variants.
(1991)
DNase activity of Costa Rican crotaline snake venoms from the genera Bothrops, Crotalus and Lachesis was quantified by an enzymodiffusion method on agarose/DNA gels containing ethidium bromide. The reaction is detected as ...
Aplicación del método de coagulación de plasma al estudio ultraestructural de especímenes biológicos
(1991)
Biological particulate specimens, including Saccharomyces cerevisiae yeast, bovine spermatozoa and human blood cells (normal erythrocytes and leukemic cells) were processed for scanning and transmission electron microscopy ...
An electrophoretic study on phospholipase A2 isoenzymes in the venoms of Central American crotaline snakes
(1992)
The number and isoelectric points of phospholipase A2 isoenzymes were studied in the venoms of 12 Central American crotaline snakes of the genera Bothrops, Crotalus, Lachesis and Agkistrodon. The study was carried out by ...
High quality 3C de novo assembly and annotation of a multidrug resistant ST-111 Pseudomonas aeruginosa genome: Benchmark of hybrid and non-hybrid assemblers
(2020)
Genotyping methods and genome sequencing are indispensable to reveal genomic structure of bacterial species displaying high level of genome plasticity. However, reconstruction of genome or assembly is not straightforward ...
Welcome to the Atta world: A framework for understanding the effects of leaf‐cutter ants on ecosystem functions
(2019)
1. Leaf‐cutter ants are a prominent feature in Neotropical ecosystems, but a comprehensive assessment of their effects on ecosystem functions is lacking. We reviewed the literature and used our own recent findings to ...