• Characterization and functional analysis of the proteins Prohibitin 1 and 2 in Trypanosoma cruzi 

      Ibarrola Vanucci, Ana Karina; De Pablos Torró, Luis Miguel; Retana Moreira, Lissette; Cornet Gómez, Alberto; Cruz Bustos, Teresa; Schijman, Alejandro G.; Ramírez, José L.; Vílchez, Susana; Osuna Carrillo de Albornoz, Antonio (2020-04-08)
      Background: Chagas disease is the third most important neglected tropical disease. There is no vaccine available, and only two drugs are generally prescribed for the treatment, both of which with a wide range of side ...
    • Delayed oral LY333013 rescues mice from highly neurotoxic, lethal doses of Papuan Taipan (Oxyuranus scutellatus) venom 

      Gutiérrez, José María; Samuel, Stephen P.; Herrera Vega, María; Bryan Quirós, Wendy; Lomonte, Bruno; Bickler, Philip E.; Bulfone, Tommaso C.; Williams, David J. (2018)
      There is an unmet need for economical snakebite therapies with long shelf lives that are effective even with delays in treatment. The orally bioavailable, heat-stable, secretory phospholipase A2 (sPLA2) inhibitor, LY333013, ...