• MYC dosage compensation is mediated by miRNA-transcription factor interactions in aneuploid cancer 

      Acón, Man Sai; Geiß, Carsten; Torres Calvo, Jorge; Bravo Estupiñan, Diana; Oviedo Blanco, Guillermo; Arias Arias, Jorge Luis; Rojas Matey, Luis Andres; Báez Villalobos, Edwin; Vásquez Vargas, Gloriana; Oses Vargas, Yendry; Guevara Coto, José Andrés; Segura Castillo, Andrés; Siles Canales, Francisco; Quirós Barrantes, Steve; Régnier Vigouroux, Anne; Mendes, Pedro; Mora Rodríguez, Rodrigo Antonio (2021-12-17)
      We hypothesize that dosage compensation of critical genes arises from systems- level properties for cancer cells to withstand the negative effects of aneuploidy. We identified several candidate genes in cancer multiomics ...