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Neutralization of local effects of the terciopelo (Bothrops asper) venom by blood serum of the colubrid snake Clelia clelia
(1982)The neutralizing capacity of the blood serum of the non-venomous snake Clelia clelia against the hemorrhagic, edematous and myonecrotic effects of Bothrops asper venom in white mice was tested using in vitro preincubation ... -
Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom
(1998-11)Local tissue damage represents a serious consequence of Bothrops asper envenomations. It encompasses a complex series of alterations, including myonecrosis, dermonecrosis, hemorrhage and edema. Due to its rapid development ... -
Neutralization of myonecrosis, hemorrhage, and edema induced by Bothrops asper snake venom by homologous and heterologous pre-existing antibodies in mice
(1996)The ability of pre-existing antibodies to neutralize locally-acting toxins of Bothrops asper snake venom was investigated. Hemorrhage, myonecrosis, and edema were markedly reduced in actively immunized mice, although ... -
Neutralization of myotoxic phospholipases A2 from the venom of the snake Bothrops asper by monoclonal antibodies
(1992)The neutralization of two myotoxic phospholipases A2 from the venom of Bothrops asper, myotoxins I and II, by two murine monoclonal antibodies is reported. The monoclonal antibodies, MAb-3 and Mab-4, recognize different ... -
Neutralization of the cytolytic and myotoxic activities of phospholipases A2 from Bothrops asper snake venom by glycosaminoglycans of the heparin/heparan sulfate family
(1994)Basic phospholipases A2 from the venom of Bothrops asper exhibit skeletal muscle damaging activity in vivo, and cytolytic activity to a variety of cell types in culture. Glycosaminoglycans of the heparin/heparan sulfate ... -
Neutralization of the neuromuscular inhibition of venom and taipoxin from the taipan (Oxyuranus scutellatus) by F(ab0)2 and whole IgG antivenoms
(2016-01-22)The neuromuscular junction activity of Oxyuranus scutellatus venom and its presynaptic neurotoxin, taipoxin, and their neutralization by two antivenoms were examined in mouse phrenic nerve-diaphragm preparations. The action ... -
Neutralization, by a monospecific Bothrops lanceolatus antivenom, of toxic activities induced by homologous and heterologous Bothı́rops snake venoms
(1999-03)A monospecific Bothrops lanceolatus antivenom, currently used in Martinique, was tested for its efficacy in the neutralization of several toxic and enzymatic activities of the venoms of B. lanceolatus, B. atrox and B. ... -
Neutralizing capacity of a new monovalent anti-Bothrops atrox antivenom: Comparison with two commercial antivenoms
(1997-04)Three horse-derived antivenoms were tested for their ability to neutralize lethal, hemorrhagic, edema-forming, defibrinating and myotoxic activities induced by the venom of Bothrops atr-ox from Antioquia and Choco (Colombia). ... -
Neutralizing interaction between heparins and myotoxin II, a Lys-49 phospholipase A2 from Bothrops asper snake venom. Identification of a heparin-binding and cytolytic toxin region by the use of synthetic peptides and molecular modeling
(1994)Heparin binds to phospholipase A2 myotoxins from Bothrops asper snake venom, inhibiting their toxic activities. This interaction was investigated using purified myotoxin II, a Lys-49 phospholipase A2 of this venom, and a ... -
Neutralizing properties of Varespladib toward group I and II myotoxic phospholipases A2
(2019)A need exists to develop specific and clinically useful inhibitors of toxic enzymes present in snake venoms, responsible for severe tissue damage and life-threatening effects occurring in thousands of people suffering ... -
Neutropenia: un vistazo a su etiología y abordaje clínico
(2016)La neutropenia se define como un recuento absoluto de neutrófilos (RAN) menor a 1 500 células/μl. Puesto que los neutrófilos proveen protección contra una variedad amplia de hongos y bacterias, la frecuencia y la ... -
Neutrophils as Trojan Horse Vehicles for Brucella abortus Macrophage Infection
(2019-05-07)Brucella abortus is a stealthy intracellular bacterial pathogen of animals and humans. This bacterium promotes the premature cell death of neutrophils (PMN) and resists the killing action of these leukocytes. B. abortus-infected ... -
Neutrophils do not contribute to local tissue damage, but play a key role in skeletal muscle regeneration, in mice injected with Bothrops asper snake venom
(2003-10)Local tissue damage induced by crotaline snake venoms includes edema, myonecrosis, hemorrhage, and an inflammatory response associated with a prominent cellular infiltrate. The role of neutrophils in the local tissue damage ... -
New approaches & technologies of venomics to meet the challenge of human envenoming by snakebites in India
(2013-07)The direct estimate of 46,000 snakebite deaths in India in 2005 (1 for every 2 HIV/AIDS deaths), based on verbal autopsies, renders unrealistic the total of only 47,000 snakebite deaths in the whole world in 2010, obtained ... -
New Diet Quality Index of children and adolescents in Costa Rica
(2020)Introduction: There is an increasing interest in the study of indicators of the quality of the total diet through the study of food groups of certain dietary patterns. Objective: Analyze the diet of students of Costa Rica ... -
New insights into the phylogeographic distribution of the 3FTx/PLA2 venom dichotomy across genus Micrurus in South America
(2019)Micrurus is a monophyletic genus of venomous coral snakes of the family Elapidae. The ~80 recognized species within this genus are endemic to the Americas, and are distributed from southeastern United States to ... -
Nickel Biosorption by Acinetobacter Baumannii and Pseudomonas Aeruginosa Isolated from Industrial Wastewater
(2006-12)Nickel biosorption ability was evaluated in two bacterial strains: Acinetobacter baumannii UCR-2971 and Pseudomonas aeruginosa UCR-2957, resulting in greatest adsorption at pH 4.5 and a residence time of 100 minutes. ... -
El Niño Southern Oscillation and vegetation dynamics as predictors of dengue fever cases in Costa Rica
(2009-03-04)Dengue fever (DF) and dengue hemorrhagic fever (DHF) are growing health concerns throughout Latin America and the Caribbean. This study focuses on Costa Rica, which experienced over 100 000 cases of DF/DHF from 2003 to ... -
Niveles de inmunoglobulinas séricas (IgG, IgA e IgM) en adultos jóvenes sanos, por el método de inmunodifusión radial
(1985)Se determinó la concentración de IgG, IgA, e IgM en el suero de 49 estudiantes universitarios normales, de 18 a 25 años. Para esto se empleó el método de inmunodifusión radial, en placas comerciales. Los resultados fueron ... -
Niveles séricos de homocisteína total y lipoproteínas en adultos jóvenes de áreas rurales y urbanas de Costa Rica
(2006)Se estudió el perfil de Iípidos y los niveles séricos de homocisteína total de una población de 400 adultos con edades entre 20 y 40 anos residentes de áreas rurales y urbanas del valle central de Costa Rica. Los resultados ...