Mostrando ítems 596-615 de 1168
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Immunological cross-recognition and neutralization studies of Micrurus mipartitus and Micrurus dumerilii venoms by two therapeutic equine antivenoms
(2020)New world Coral snakes comprise 82 species of medical importance distributed from southeastern United States to Argentina. In Colombia, Micrurus mipartitus and M. dumerilii are responsible for most coral snakebite accidents. ... -
Immunological studies on BaH1 and BaPI, two hemorrhagic metalloproteinases from the venom of the snake Bothrops asper
(1995-08)No immunological cross-reactivity was observed between BaH1 and BaP1, two hemorrhagic metalloproteinases isolated from B. asper venom, by gel immunodiffusion, Western blotting and neutralization studies. Cross-reactivity ... -
Impact of Regional Variation in Bothrops asper Snake Venom on the Design of Antivenoms: Integrating Antivenomics and Neutralization Approaches
(2010-10-21)Intraspecific snake venom variations have implications in the preparation of venom pools for the generation of antivenoms. The impact of such variation in the cross-reactivity of antivenoms against Bothrops asper venom was ... -
El impacto de la resistencia a los antibióticos en el desarrollo sostenible
(2022)La resistencia a los antimicrobianos (RAM) es un problema de salud pública cada vez más complejo y se considera como una de las mayores amenazas en todo el mundo. El desarrollo de la RA en los patógenos bacterianos es una ... -
Impacto de una iniciativa de participación comunitaria sobre los índices larvales tradicionales para Ae. Aegypti (Diptera: culicidae) en una comunidad urbana en riesgo de dengue en San José, Costa Rica
(2007-06-01)Introducción. El impacto sobre los índices larvales tradicionales para Aedes aegypti: índice de viviendas (IV), índice de contenedores (IC) e índice de Breteau (IB) fue evaluado tras la implementación de una iniciativa de ... -
Implementación de un laboratorio de análisis proteómicos en el Instituto Clodomiro Picado (UCR): primeras experiencias en Costa Rica
(2012)Reseña sobre avances tecnológicos en la implementación de un laboratorio de análisis proteómico en Costa Rica. Se describe la espectrometría de masas, la ionización de muestra, la instrumentación básica, la espectrometría ... -
Importance of mevalonate pathway lipids on the growth and survival of primary and metastatic gastric carcinoma cells
(2021)Purpose: This preclinical study aims to determine the effect of drugs that alter isoprenoids and cholesterol metabolism in the homeostasis of gastric carcinoma cell lines in the search for new therapeutic targets for stomach ... -
Importancia del laboratorio clínico en el éxito de los trasplantes de células madre hematopoyéticas
(2021)El trasplante de células madre hematopoyéticas es la única terapia curativa tanto para desordenes hereditarios que afectan la médula ósea como para enfermedades adquiridas, el procedimiento consiste en reponer células madre ... -
Improved biomass and protein production in solid-state cultures of an Aspergillus sojae strain harboring the Vitreoscilla hemoglobin
(2015-07-30)The biotechnological value of Aspergillus sojae ATCC 20235 (A. sojae) for production of pectinases in solidstate fermentation (SSF) has been demonstrated recently. However, a common drawback of fungal solid-state cultures ... -
Improving antivenom availability and accessibility: Science, technology, and beyond
(2012-09-15)Snakebite envenomings constitute a serious and neglected public health problem. Despite the fact that effective treatment exists, i.e. administration of animal-derived antivenoms, the availability and accessibility of these ... -
In vitro activity of BaH1, the main hemorrhagic toxin of Bothrops asper snake venom on bovine endothelial cells
(1995-10)Incubation of BaH1, the main hemorrhagic toxin purified from the venom of Bothrops asper, with endothelial cells caused the appearance of spaces among the cells. This effect became more noticeable with increasing hemorrhagin ... -
In vitro Characterization of Anti-SARS-CoV-2 Intravenous Immunoglobulins (IVIg) Produced From Plasma of Donors Immunized With the BNT162b2 Vaccine and Its Comparison With a Similar Formulation Produced From Plasma of COVID-19 Convalescent Donors
(2022)Despite vaccines are the main strategy to control the ongoing global COVID-19 pandemic, their effectiveness could not be enough for individuals with immunosuppression. In these cases, as well as in patients with ... -
In vitro discovery of a human monoclonal antibody that neutralizes lethality of cobra snake venom.
(2022)The monocled cobra (Naja kaouthia) is among the most feared snakes in Southeast Asia due to its toxicity, which is predominantly derived from long-chain α-neurotoxins. The only specific treatment for snakebite envenoming ... -
In vitro effects of environmental isolates of Acanthamoeba T4 and T5 over human erythrocytes and platelets
(2020-01-21)Free-living amoebae of the genus Acanthamoeba have been associated with keratitis and encephalitis. Some factors related to their pathogenic potential have been described, including the release of hydrolytic enzymes, and ... -
In Vitro Inhibition of Zika Virus Replication with Amantadine and Rimantadine Hydrochlorides
(2021-09-15)Zika virus (ZIKV) is a mosquito-borne flavivirus in which human infection became relevant during recent outbreaks in Latin America due to its unrecognized association with fetal neurological disorders. Currently, there ...