Listar Microbiología por título
Mostrando ítems 212-231 de 1168
-
Caracterización proteómica, funcional e inmunoneutralización del veneno de la serpiente Porthidium porrasi de Costa Rica
(2019-10)Con el fin de generar conocimiento de base sobre los venenos de las serpientes que habitan Costa Rica, en este proyecto se realizó la caracterización proteómica, funcional e inmunoneutralización del veneno de la serpiente ... -
Características físicas, químicas y microbiológicas del agua subterránea en Los Chiles, Costa Rica, y su asociación con el uso del suelo
(2023)Introduction: Los Chiles has one of the lowest Social Progress Indexes in Costa Rica. The inhabitants drink untreated groundwater from an aquifer across the Nicaragua-Costa Rica border. Objective: To characterize water ... -
Cardiac effect induced by Crotalus durissus cascavella venom: morphofunctional evidence and mechanism of action
(2021)Envenoming, resulting from snake bites, is a global public health problem. The present study was undertaken to investigate the influence of Crotalus durissus cascavella (Cdcas) venom on cardiac activity and the mechanisms ... -
Caso clínico: Rinoescleroma
(2013-01)The case of a 19–year–old male patient from a rural area is presented. He had a 3-year history of nasal obstruction, episodes of facial inflammation, epistaxis, fetid rhinorrhea, hearing loss in the right ear, bilateral ... -
Catalytically inactive phospholipase A2 homologue binds to vascular endothelial growth factor receptor-2 via C-terminal loop region
(2008)VEGF (vascular endothelial growth factor) regulates neovascularization through binding to its receptorKDR(kinase insert domaincontaining receptor; VEGF receptor-2). We recently identified a catalytically inactive PLA2 ... -
Cálculo de la actividad hemolítica del complemento sérico (CH50) mediante un programa en "BASIC": Comparación con el método gráfico manual.
(1986)En el presente trabajo se describe el programa para el cálculo de la actividad hemolítica del complemento sérico, y se muestran los resultados de un estudio comparativo entre el método gráfico manual y el método matemático ... -
Cell surface nucleolin interacts with and internalizes Bothrops asper Lys49 phospholipase A2 and mediates its toxic activity
(2018)Phospholipases A2 are a major component of snake venoms. Some of them cause severe muscle necrosis through an unknown mechanism. Phospholipid hydrolysis is a possible explanation of their toxic action, but catalytic and ... -
Cellular pathology induced by snake venom phospholipase A2 myotoxins and neurotoxins: common aspects of their mechanisms of action
(2008-06-20)A large variety of snake toxins evolved from PLA2 digestive enzymes through a process of ‘accelerated evolution’. These toxins have different tissue targets, membrane receptors and mechanisms of alteration of the cell ... -
Challenges detecting SARS-CoV-2 in Costa Rican domestic wastewater and river water
(2023-11-01)This study presents the development of a SARS-CoV-2 detection method for domestic wastewater and river water in Costa Rica, a middle-income country in Central America. Over a three-year period (November to December 2020, ... -
Chapter 11: Antiviral, Antimicrobial, and Antibiofilm Properties of Biosurfactants
(2021-04-01)In an era of increasing drug resistance, the search for antimicrobial agents is crucial for the development of a sustainable future. Biosurfactants are amphiphilic molecules with recognised surface tension, and biological ... -
Characterization and functional analysis of the proteins Prohibitin 1 and 2 in Trypanosoma cruzi
(2020-04-08)Background: Chagas disease is the third most important neglected tropical disease. There is no vaccine available, and only two drugs are generally prescribed for the treatment, both of which with a wide range of side ... -
Characterization of 'basparin A,' a prothrombin-activating metalloproteinase, from the venom of the snake Bothrops asper that inhibits platelet aggregation and induces defibrination and thrombosis
(2003-10)A prothrombin activator, named ‘basparin A,’ was isolated from the venom of the crotaline snake Bothrops asper, the species responsible for the majority of snakebite cases in Central America. It is an acidic (pI 5.4), 70 ... -
Characterization of a basic phospholipase A2-homologue myotoxin isolated from the venom of the snake Bothrops neuwiedii (yarará chica) from Argentina
(1999)A basic protein was isolated by CM-Sephadex C-25 chromatography from the venom of Bothrops neuwiedii from Argentina, and named B. neuwiedii myotoxin I. This protein exerted local myotoxic and edema-forming e ects in mice, ... -
Characterization of a novel snake venom component: Kazal-type inhibitor-like protein from the arboreal pitviper Bothriechis schlegelii
(2016-06)Snake venoms are composed mainly of a mixture of proteins and peptides. Notably, all snake venom toxins have been assigned to a small number of protein families. Proteomic studies on snake venoms have recently identified ... -
Characterization of alpha-neurotoxin and phospholipase A2 activities from Micrurus venoms. Determination of the amino acid sequence and receptor-binding ability of the major alpha-neurotoxin from Micrurus nigrocinctus nigrocinctus
(1996)New World elapids are coral snakes that belong to the genus Micrurus, and for which the venom biochemistry is mostly unknown. Analysis has been difficult because the coral snakes produce small quantities of venom. Clinical ... -
Characterization of aspercetin, a platelet aggregating component from the venom of the snake Bothrops asper which induces thrombocytopenia and potentiates metalloproteinase-induced hemorrhage
(2001-04)Thrombocytopenia occurs in a number of patients bitten by Bothrops asper, a species responsible for the majority of snakebites in Central America and southern Mexico. In this work we describe the isolation of a new ... -
Characterization of events associated with apoptosis/anoikis induced by snake venom metalloproteinase BaP1 on human endothelial cells
(2005-02)Human endothelial EA.hy926 cells were incubated with BaP1, a hemorrhagic metalloproteinase purified from Bothrops asper snake venom. Since the first hour of incubation with the proteinase, cells started showing DNA ... -
Characterization of Extracellular Vesicles Secreted by a Clinical Isolate of Naegleria fowleri and Identification of Immunogenic Components within Their Protein Cargo
(2022-06)Abstract: Extracellular vesicles (EVs) are small lipid vesicles released by both prokaryotic and eu-karyotic cells, involved in intercellular communication, immunomodulation and pathogenesis. In this study, we performed a ...