Browsing Microbiología by Title
Now showing items 152-171 of 946
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Calcium imaging of muscle cells treated with snake myotoxins reveals toxin synergism and presence of acceptors
(2009-04-17)Snake myotoxins have a great impact on human health worldwide. Most of them adopt a phospholipase A2 fold and occur in two forms which often co-exist in the same venom: the Asp49 toxins hydrolyse phospholipids, whilst Lys49 ... -
Calcium ion independent membrane leakage induced by phospholipase-like myotoxins
(1992-12)The two snake venom myotoxins ammodytin L and myotoxin II, purified respectively from Vipera ammodytes ammodytes and Bothrops asper, have phospholipase-like structures but lack an Asp-49 in the active site and are without ... -
Calcium plays a key role in the effects induced by a snake venom Lys49 phospholipase A2 homologue on a lymphoblastoid cell line
(2006-01)A catalytically-inactive Lys49 phospholipase A2 homologue from the venom of the snake Bothrops asper induces diverse effects (necrosis, apoptosis and proliferation) in a lymphoblastoid cell line, depending on the toxin ... -
Cambios en el patrón electroforético del veneno de cascabela muda (Lachesis muta stenophrys) durante el almacenamiento bajo diferentes condiciones
(1985)Liquid and lyophilized samples of Lachesis muta venom were stored at different temperatures and for different periods of time, and analyzed by polyacrylamide gel electrophoresis (PAGE) and immunoelectrophoresis. Only slight ... -
Cambios post mortem en mucosa intestinal y tejido pulmonar de Mus musculus, observados al microscopio electrónico de barrido
(Revista de Biología Tropical 29(2) p.265-272, 1981)Post mortem ultrastructural alterations of surface epithelial tissues were studied by scanning electron microscopy. Ten male albino mice were sacrificed, and the duodenum, ileum arid lung excised and fixed immediately, ... -
‘Candidatus Rickettsia nicoyana’: A novel Rickettsia species isolated from Ornithodoros knoxjonesi in Costa Rica
(2017-06)Rickettsiae are intracellular bacteria commonly associated with hematophagous arthropods. Most of them have been described in hard ticks, but some have been found in soft ticks. Here we report the detection and isolation ... -
Caprylic acid fractionation of hyperimmune horse plasma: description of a simple procedure for antivenom production
(1994)A simple methodology for hyperimmune horse plasma fractionation, based on caprylic acid precipitation, is described. Optimal conditions for fractionation were studied; the method gives best results when concentrated caprylic ... -
Caracterización clínica y de los hallazgos en líquido cefalorraquídeo, de pacientes inmunocompetentes e inmunosupresos, con meningitis o encefalitis viral, diagnosticados por métodos moleculares en el Hospital San Juan de Dios, en el período de enero del 2018 a junio del 2020
(2021-03)Justificación y objetivos: Las infecciones del Sistema Nervioso Central suponen un problema importante de salud. En Costa Rica, existen vacíos importantes en torno a los datos de los casos de meningitis y encefalitis de ... -
Caracterización de los sitios de multiplicación de Aedes aegypti (Diptera: Culicidae) en el caserío “La Carpio”, San José, Costa Rica durante la estación seca del 2003
(2004-06-01)El primer brote de dengue en San José, la capital de Costa Rica, fue documentado hasta el año 2002 en la comunidad La Carpio, donde las condiciones climáticas y sociales son adecuadas para la transmisión viral. La ... -
Caracterización proteómica y toxicológica del veneno de Crotalus pifanorum (viperidae) y evaluación de su uso como inmunógeno sobre la respuesta por anticuerpos contra co-inmunógenos y venenos de otros crótalos americanos
(2019)En Costa Rica se produce un antiveneno poliespecífico (PoliVal-ICP) usando como inmunógenos los venenos de las serpientes Bothrops asper, Crotalus simus y Lachesis stenophrys. Este antiveneno es capaz de neutralizar a la ... -
Caracterización proteómica, funcional e inmunoneutralización del veneno de la serpiente Porthidium porrasi de Costa Rica
(2019-10)Con el fin de generar conocimiento de base sobre los venenos de las serpientes que habitan Costa Rica, en este proyecto se realizó la caracterización proteómica, funcional e inmunoneutralización del veneno de la serpiente ... -
Cardiac effect induced by Crotalus durissus cascavella venom: morphofunctional evidence and mechanism of action
(2021)Envenoming, resulting from snake bites, is a global public health problem. The present study was undertaken to investigate the influence of Crotalus durissus cascavella (Cdcas) venom on cardiac activity and the mechanisms ... -
Catalytically inactive phospholipase A2 homologue binds to vascular endothelial growth factor receptor-2 via C-terminal loop region
(2008)VEGF (vascular endothelial growth factor) regulates neovascularization through binding to its receptorKDR(kinase insert domaincontaining receptor; VEGF receptor-2). We recently identified a catalytically inactive PLA2 ...