Listar Microbiología por autor "bd1f3c31-8aab-46a3-8bd0-15767c6754d0"
Mostrando ítems 1-5 de 5
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An overview of Lysine-49 phospholipase A2 myotoxins from crotalid snake venoms and their structural determinants of myotoxic action
Lomonte, Bruno; Angulo Ugalde, Yamileth; Calderón Fuentes, Leonel (2003)In 1984, the first venom phospholipase A2 (PLA2) with a lysine substituting for the highly conserved aspartate 49 was discovered, in the North American crotalid snake Agkistrodon p. piscivorus [J. Biol. Chem. 259 (1984) ... -
Biological and biochemical activities of Vipera berus (European viper) venom
Calderón Fuentes, Leonel; Lomonte, Bruno; Gutiérrez, José María; Tarkowski, Andrej; Hanson, Lars Ake (1993-06)Vipera berus is widely distributed throughout the northern part of Europe and Asia. Characterization of several toxic effects of its venom in the mouse, as well as of in vitro enzymatic activities was performed. Vipera ... -
Immunochemical characterization and role in toxic activities of region 115-129 of myotoxin II, a Lys49 phospholipase A2 from Bothrops asper snake venom
Calderón Fuentes, Leonel; Lomonte, Bruno (1998-10)The region 115–129 of myotoxin II, a catalytically inactive Lys49 phospholipase A2, was previously shown to constitute a heparin-binding site and to be involved in its cytolytic action in vitro. An immunochemical ... -
Inhibition of the myotoxic activity of Bothrops aspermyotoxin II in mice by immunization with its synthetic 13-mer peptide 115-129
Calderón Fuentes, Leonel; Lomonte, Bruno (1999)The region comprising amino acid residues 115±129 of myotoxin II, a Lys49 phospholipase A2 from the venom of Bothrops asper, was previously shown to constitute a heparin binding site, and to be associated with its toxic ... -
Quantitation by enzyme-immunoassay of antibodies against Bothrops myotoxins in four commercially-available antivenoms
Lomonte, Bruno; Gutiérrez, José María; Rojas Céspedes, Gustavo; Calderón Fuentes, Leonel (1991)An enzyme-immunoassay (EIA) for the quantitation of antibodies against myotoxins present in the venoms of Bothrops asper (Costa Rica), B. atrox (Colombia) and B. moojeni (Brazil), was developed. This EIA was utilized for ...