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Life-course BMI and biomarkers in persons aged 60 years or older: a comparison of the USA and Costa Rica

Rehkopf, David H.; Duong, Andrew; Dow, William H.; Rosero Bixby, Luis (2019)

Objective: There is a large literature linking current body mass index (BMI) to levels of cardiovascular risk biomarkers, but it is unknown whether measures of BMI earlier in the life course and maximum BMI are predictive ...

Costa Rican Longevity and Healthy Aging Study

Rosero Bixby, Luis; Dow, William H.; Brenes Camacho, Gilbert (2019)

The Costa Rican Longevity and Healthy Aging Study (CRELES, or Costa Rica Estudio de Longevidad y Envejecimiento Saludable) is a set of nationally representative longitudinal surveys of health and life-course experiences ...

Correlates of longitudinal leukocyte telomere length in the Costa Rican Longevity Study of Healthy Aging (CRELES): On the importance of DNA collection and storage procedures

Rosero Bixby, Luis; Rehkopf, David H.; Dow, William H.; Lin, Jue; Epel, Elissa S.; Azofeifa Navas, Jorge; Leal Esquivel, Alejandro (2019)

The objective is to identify cofactors of leukocyte telomere length (LTL) in a Latin American population, specifically the association of LTL with 36 socio-demographic, early childhood, and health characteristics, as well ...

Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity.

Dec, Eric; Clement, James; Cheng, Kaiyang; Church, George M.; Fossel, Michael B.; Rehkopf, David H.; Rosero Bixby, Luis; Kobor, Michael S.; Lin, David TS.; Lu, Ake T.; Fei, Zhe; Guo, Wei; Chew, Yap Ching; Yang, Xiaojing; Dwi Putra, Sulistyo E.; Reiner, Alex P.; Correa, Adolfo; Vilalta, Adrian; Pirazzini, Chiara; Passarino, Giuseppe; Monti, Daniela; Arosio, Beatrice; Garagnani, Paolo; Franceschi, Claudio; Horvath, Steve (2023)

Claims surrounding exceptional longevity are sometimes disputed or dismissed for lack of credible evidence. Here, we present three DNA methylation-based age estimators (epigenetic clocks) for verifying age claims of ...

Estacionalidad de la mortalidad en los trópicos. El caso de Costa Rica, 1970-2016
Seasonal Variation of Mortality in the Tropics. The Case of Costa Rica, 1970-2016

Rosero Bixby, Luis; Santamaría Ulloa, Carolina (2019)

El objetivo de esta investigación es determinar la existencia y magnitud de ciclos de variación estacional en la mortalidad de Costa Rica de 1970 a 2016. Metodológicamente, el estudio se basa en microdatos de 630,000 ...