Clase 1 integrase ang genetic cassettes blaoxa and blatem among multidrug resistant Shigella isolates in Costa Rica
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Date
2014Author
Barrantes Jiménez, Kenia
Chacón Jiménez, Luz María
Solano Barquero, Melissa
Achí Araya, María Rosario
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Shigella is an important enteropathogen and the major cause of dysentery and
diarrheal disease around the world. There are no studies related to the molecular
detection of integrons among Shigella spp. isolates in Costa Rica. Here we are
reporting for the first time the presence of class 1 integrase (intI-1) and extended
spectrum β-lactamases genetic cassettes, blaOXA, and blaTEM among multidrug
resistant Shigella isolates in Costa Rica. The antibiotic resistance pattern and
presence of integrase class 1(intI-1) and genetic cassettes blaOXA and blaTEM were
analyzed in 30 Shigella isolates (S. flexneri (83%) and S. sonnei (17%). Bacteria
were collected at hospitals and cliniques in Costa Rica and exclusively from
stools of individuals with diarrhea. from Costa Rica. Twenty nine out of 30
isolates were resistant to at least, one antibiotic. Multidrug resistance was
observed in 26 out of 30 isolates (87%), and found to carry integrase class 1
(93%), and genetic cassettes blaOXA (76%) and blaTEM (7%).
Artículo científico -- Universidad de Costa Rica. Instituto de Investigaciones en Salud, 2014