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Mostrando ítems 11-20 de 423
Ending the drought: New strategies for improving the flow of affordable, effective antivenoms in Asia and Africa
(2011-08-24)
The development of snake antivenoms more than a century ago should have heralded effective treatment of the scourge of snakebite envenoming in impoverished, mostly rural populations around the world. That snakebite still ...
Local effects induced by coral snake venoms: Evidence of myonecrosis after experimental inoculations of venoms from five species
(1983)
The local effects induced by intramuscular inoculations of venons from six species of coral snakes were studied in mice. Venoms of Micrurus nlgrocinctus nigrocinctus, M. n . moquitensis, M. alleni, M. frontalis, M. aarinkauda ...
Proteomic and toxicological analysis of the venom of Micrurus yatesi and its neutralization by an antivenom
(2022)
Coralsnakes belong to the family Elapidae and possess venoms which are lethal to humans and can be grouped based on the predominance of either three finger toxins (3FTxs) or phospholipases A2 (PLA2s). A proteomic and ...
Snake venom phospholipase A2s (Asp49 and Lys49) induce mechanical allodynia upon peri-sciatic administration: involvement of spinal cord glia, proinflammatory cytokines and nitric oxide
(2004-03)
Snakebites constitute a serious public health problem in Central and South America, where species of the lancehead pit vipers (genus Bothrops) cause the majority of accidents. Bothrops envenomations are very painful, and ...
El suero antiofídico polivalente producido en Costa Rica: Estabilidad y capacidad neutralizante
(1988)
En este trabajo se revisan y discuten una serie
de aspectos relativos a la producción,
estabilidad y capacidad neutralizante del suero
antiofídico polivalente producido por el Instituto
Clodomiro Picado. Este suero ...
Neutrophils do not contribute to local tissue damage, but play a key role in skeletal muscle regeneration, in mice injected with Bothrops asper snake venom
(2003-10)
Local tissue damage induced by crotaline snake venoms includes edema, myonecrosis, hemorrhage, and an inflammatory response associated with a prominent cellular infiltrate. The role of neutrophils in the local tissue damage ...
Inhibition of Myotoxic Activity of Bothrops asper Myotoxin II by the Anti-trypanosomal Drug Suramin
(2005-06-15)
Suramin, a synthetic polysulfonated compound, developed initially for the treatment of African trypanosomiasis and onchocerciasis, is currently used for the treatment of several medically relevant disorders. Suramin, ...
Venomics of new world pit vipers: genus-wide comparisons of venom proteomes across Agkistrodon
(Journal of Proteomics vol 96, p.103-116, 2014-01-16)
Wereport a genus-wide comparison of venomproteomevariation acrossNewWorld pit vipers in the genus Agkistrodon. Despite the wide variety of habitats occupied by this genus and that all its taxa feed on diverse species of ...
Effect of Bothrops asper (Fer-De-Lance) snake venom on erythrocyte membrane. A comparative study
(1992-02)
1. The effect of Bothrops asper venom on erythrocytes of different species, sheep erythrocyte ghost vesicles and liposomes made of phospholipids from sheep erythrocytes was studied. 2. B. asper venom had a direct hemolytic ...
Snake Venomics of the Lesser Antillean Pit Vipers Bothrops caribbaeus and Bothrops lanceolatus: Correlation with Toxicological Activities and Immunoreactivity of a Heterologous Antivenom
(2008-10)
The venom proteomes of the snakes Bothrops caribbaeus and Bothrops lanceolatus, endemic to the
Lesser Antillean islands of Saint Lucia and Martinique, respectively, were characterized by reversephase
HPLC fractionation, ...