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Predicting Cancer Chemosensitivity Based on Intensity/Distribution Profiles of Cells Loaded with a Fluorescent Sphingolipid Analogue
(2018)
Cancer is a group of heterogeneous and complex
diseases, with limited therapeutic options due to the recurrent
emergence of drug resistance. Sphingolipids are bioactive
molecules that participate in signaling of cell ...
Evaluación del poder antioxidante, propiedades fisicoquímicas y composición fitoquimica de extractos de semilla de bactris gasipaes para formulaciones dermocosméticas
Evaluation of the antioxidant power, physicochemical properties and phytochemical composition of seed extracts of bactris gasipaes for dermocosmetic formulations
(2019)
Bactris gasipaes es una palmera de la cual se obtiene una fruta conocida comúnmente
en Costa Rica como Pejibaye, es autóctona de América Central, muy común en la alimentación de
Costa Rica, por su alto contenido de almidón ...
Comparison of Tropical and Temperate Zone Diarrheal Problems
(1978)
In the past. we thought there were differences hetween tropica! and temperate
zones in the etiology of intestinal diseases. Recent observations indicate that
such differences do not exist. Infectious agents are ubiquitous. ...
Hybrid mathematical modeling decodes the complexity of sphingolipid pathway to predict chemosensitivity
(2017)
Sphingolipid (SL) signaling pathway is a complex
biological system able to integrate different types of cellular
stress signals related to induction of cell death pathways with
special interest in cancer. This makes of ...
Investing in education and health versus militarism: the case of Costa Rica
(IPPNW Report [International Physicians for Prevention of Nuclear War, Boston] Report 2(3):22 -25, 1984)
Costa Rica has a rather humble ancestry of tribal aborigines blended with poor and mostly illiterate colonizing Spaniards, and with a later and very modest immigration of other Europeans. A rural agricultural society ...
Characterization of heterogeneous response to chemotherapy by perturbation-based modeling of fluorescent sphingolipid metabolism in cancer cell subpopulations
(2017)
Cancer treatments options are limited by the generation of therapy resistance, which is due by intratumoral heterogeneity in cell response. The study of resistance requires biosensors able to report the response at the ...
Identification of cancer chemosensitivity by ODE and GMM modeling of heterogeneous cellular response to perturbations in fluorescent sphingolipid metabolism
(2016-11-11)
Cancer refers to a group of diseases in which cells display uncontrolled growth. Chemotherapy options are usually conditioned by generating resistance which is explained in part by the intrinsic heterogeneity of the ...
Shigellosis in Central America
(Shigellosis: a continuing global problem:ICDDR,Bangladesh p 26-38, 1983)
Shigella infections are very common in Central America, except in Costa
Rica and Panama where prevalence rates are low. Shigellosis is the most
serious among all the specific diarrhoeas, due to its invasive character,
systemic ...