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Patient Organizations’ Barriers in Pharmacovigilance and Strategies to Stimulate Their Participation
(2020)
European drug regulations aim for a patient-centered approach, including involving patients in the pharmacovigilance (PV) systems. However many patient organizations have little experience on how they can participate in ...
Venom diversity in the neotropical genus Tityus: implications for antivenom design emerging from molecular and immunochemical analyses across endemic areas of scorpionism
(2020)
Scorpions of the Neotropical genus Tityus are responsible for most severe envenomations in the Caribbean, South America, and Lower Central America (LCA). Although Tityus is taxonomically complex, contains high toxin ...
Detection of Dirofilaria immitis and other arthropod-borne filarioids by an HRM real-time qPCR, blood-concentrating techniques and a serological assay in dogs from Costa Rica
(2015)
Background: Canine filarioids are important nematodes transmitted to dogs by arthropods. Diagnosis of canine
filariosis is accomplished by the microscopic identification of microfilariae, serology or PCR for filarial-DNA. ...
Tratamientos COVID-19
(2020)
El ensayo inmunosorbente enzima conjugada (ELISA) en el diagnóstico de rotavirus
(1977)
La creciente importancia que los rotavirus tienen en: las llamadas diarreas inespecíficas (3,6) ha llevado al desarrollo de diversas técnicas de laboratorio para estudiar el papel de esos vírus en la etiología de la diarrea. ...
Potent virucidal activity against Flaviviridae of a group IIA phospholipase A2 isolated from the venom of Bothrops asper
(2020)
Secreted phospholipase A2 (sPLA2) molecules are small, calcium-dependent enzymes involved in many biological processes. Viperid venoms possess gIIA sPLA2s and sPLA2-like proteins, both having homology to human gIIA sPLA2, ...
Physical characteristics of nano-Hydroxyapatite Pickering-emulsions and their adjuvant activity on the antibody response towards the Bothros asper snake venom
(2019)
Emulsions are crucial in the treatment of snake bites to bust the antibody response of the inmunogen. The widely used Freund's emulsion typically combines 50/50 water-oil (W/O) phase. However, its use is limited because ...
Snake venomics, experimental toxic activities and clinical characteristics of human envenomation by Bothrocophias myersi (Serpentes: Viperidae) from Colombia
(2020)
Venoms of the viperid genus Bothrocophias, restricted to Colombia and Ecuador, are poorly known. Only a proteomic analysis of B. campbelli venom has been described. In this work we present a proteomic study of B. myersi ...