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Structural and functional characterization of myotoxin I, a Lys49 phospholipase A(2) homologue from Bothrops moojeni (Caissaca) snake venom
(2000-01-01)
Myotoxin-I (MjTX-I) was purified to homogeneity from the venom of Bothrops moojeni by ion-exchange chromatography on CM-Sepharose. Its molecular weight, estimated by SDS–PAGE, was 13,400 (reduced) or 26,000 (unreduced). ...
Phospholipase A2 myotoxins from Bothrops snake venoms
(1995-11)
The genus Bothrops is distributed over all Latin America, From Mexico to Argentina, and comprises nearly 31 species of snake. In most of these countries, Bothrops spp. cause the majority of snake bit envenomations, which ...
Actividad letal de seis venenos de serpientes de importancia médica en el Ecuador
(2016-11)
Se determinó la actividad letal de los venenos de serpientes de seis especies de vipéridos colectadas en Ecuador, a través de ratones CD-1. La especie más abundante fue Bothrops asper de la cual se analizaron adultos y ...
Systemic cytokine response in children bitten by snakes in Costa Rica
(2001-12)
BACKGROUND:
To characterize the host response to venom from snakes of the family Viperidae in Costa Rica, we investigated the release of cytokines: IL-1, IL-6, IL-8, TNF-alpha, MIP-1beta, and RANTES in pediatric patients ...
Biochemical characterization of the venom of Central American scorpion Didymocentrus krausi Francke, 1978 (Diplocentridae) and its toxic effects in vivo and in vitro
(2019)
non-buthid venoms, for which knowledge is scarce. In this work, we characterized the venom of a Diplocentridae
species, Didymocentrus krausi, a small fossorial scorpion that inhabits the Tropical Dry Forest of Central ...
Neutralizing properties of Varespladib toward group I and II myotoxic phospholipases A2
(2019)
A need exists to develop specific and clinically useful inhibitors of toxic enzymes present in snake venoms,
responsible for severe tissue damage and life-threatening effects occurring in thousands of people suffering
...
Computational Biology in Costa Rica: the role of a small country in the global context of bioinformatics
(2008)
Introduction: The successful development of high throughput methods for DNA sequencing, transcriptomics, proteomics, and other –omics, has contributed to the emergence of novel possibilities for the examination of complex ...
Ontogenetic changes in the venom of the snake Lachesis muta stenophrys (bushmaster) from Costa Rica
(1990)
A comparative study was performed on some enzymatic and toxic activities of venoms collected from newborn, one-year old, two-years old and adult (more than five-years old) specimens of Lachesis muta stenophrys. There was ...
Snake Venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus Complex Points to Neurotoxicity as an Adaptive Paedomorphic Trend along Crotalus Dispersal in South America
(2010)
We report a comparative venomic and antivenomic characterization of the venoms of newborn and adult specimens of the Central American rattlesnake, Crotalus simus, and of the subspecies cumanensis, durissus, ruruima, and ...
Individual expression patterns of myotoxin isoforms in the venom of the snake Bothrops Asper.
(1992)
In order to investigate the distribution of myotoxin isoforms in the snake Bothrops asper,
venoms from individual specimens were analyzed by a cathodic electrophoretic system for basic proteins
under native conditions.The ...