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Menopause, A Universal Female Experience: Lessons from Mexico and Central America 

Locklear, Tracie D.; Doyle, Brian J.; Huang, Yue; Pérez Sánchez, Alice Lorena; Caceres, Armando; Mahady, Gail B. (Current Women’s Health Reviews 4(1), 3-8, 2008)
In Mexico and Central America, women typically experience menopause up to 10 years earlier than their U.S. counterparts. This may be due in part to numerous pregnancies, long periods of lactation, poor nutrition, extreme ...
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Aud-SWIPE-P: A parallelization of the Aud-SWIPE pitch estimation algorithm using multiple processes and threads 

Camacho Lozano, Arturo; Calderón Ramírez, Saúl; Alvarado Méndez, Gabriel (Acta Press. Artificial Intelligence and Applications / 794: Modelling, Identification and Control / 795: Parallel and Distributed Computing and Networks / 796: Software Engineering / 792: Web-based Education (AIA 2013), 2013-02-11)
In this work we implement a parallel version of the pitch estimation algorithm Aud-SWIPE. The new implementation, Aud-SWIPE-P produces a remarkable acceleration, making it usable in applications where it was not efficient ...

Dissociation of enzymatic and pharmacological properties of piratoxins-I and -III, two myotoxic phospholipases A2 from Bothrops pirajai snake venom 

Soares, Andreimar Martins; Andrião Escarso, Silvia H.; Bortoleto, Raquel K.; Rodrigues Simioni, Lea; Arni, Raghuvir K.; Ward, Richard John; Gutiérrez, José María; Giglio, José Roberto (2001-03-15)
Piratoxins (PrTX) I and III are phospholipases A2 (PLA2s) or PLA2 homologue myotoxins isolated from Bothrops pirajai snake venom, which also induce myonecrosis, bactericidal activity against Escherichia coli, disruption ...

Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants 

Chacur, Marucia; Longo, I.; Picolo, Gisele; Gutiérrez, José María; Lomonte, Bruno; Guerra, J. L.; Teixeira, Catarina de Fátima; Cury, Yara (2003-05)
The ability of Lys49 and Asp49 phospholipases A2 (PLA2), from Bothrops asper snake venom, to cause hyperalgesia was investigated in rats, using the paw pressure test. Intraplantar injection of both toxins (5–20 μg/paw) ...
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Public health implications of low birth weight 

Mata Jiménez, Leonardo; Urrutia, Juan José; Mohs Villalta, Edgar (1977)
The present paper interpets the significance of anthropometric data of newborns from a typical Indian village of Guatemala and from the general population of Costa Rica. A good correlation exists between a deficient fetal ...

Comparison between IgG and F(ab′)2 polyvalent antivenoms: neutralization of systemic effects induced by Bothrops asper venom in mice, extravasation to muscle tissue, and potential for induction of adverse reactions 

León Montero, Guillermo; Monge Monge, María; Rojas Umaña, Ermila; Lomonte, Bruno; Gutiérrez, José María (2001-06)
Whole IgG and F(ab′)2 equine-derived polyvalent (Crotalinae) antivenoms, prepared from the same batch of hyperimmune plasma, were compared in terms of neutralization of the lethal and defibrinating activities induced by ...
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Cambios en el patrón electroforético del veneno de cascabela muda (Lachesis muta stenophrys) durante el almacenamiento bajo diferentes condiciones 

Gené, José Antonio; Lomonte, Bruno; Gutiérrez, José María; Cerdas Fallas, Luis (1985)
Liquid and lyophilized samples of Lachesis muta venom were stored at different temperatures and for different periods of time, and analyzed by polyacrylamide gel electrophoresis (PAGE) and immunoelectrophoresis. Only slight ...
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A biocomputational platform for the automated construction of large-scale mathematical models of miRNA-transcription factor networks for studies on gene dosage compensation 

Acón, Man Sai; Siles Canales, Francisco; Mora Rodríguez, Rodrigo Antonio (2016-11-09)
Cancer complexity and resistance is mediated by cell-to-cell heterogeneity, which is the consequence of the enormous instability of its genetic material. It is unknown how cancer cells are able to withstand the effects ...

Danger in the reef: Proteome, toxicity, and neutralization of the venom of the olive sea snake, Aipysurus laevis 

Laustsen, Andreas Hougaard; Gutiérrez, José María; Rasmussen, Arne R.; Engmark, Mikael Gerling; Gravlund, Peter; Sanders, Kate L.; Lohse, Brian; Lomonte, Bruno (2015-12-01)
Four specimens of the olive sea snake, Aipysurus laevis, were collected off the coast of Western Australia, and the venom proteome was characterized and quantitatively estimated by RP-HPLC, SDS-PAGE, and MALDI-TOF-TOF ...

Skeletal muscle necrosis and regeneration after injection of Thalassophryne nattereri (niquim) fish venom in mice 

Lopes Ferreira, Mónica; Núñez, Javier; Rucavado Romero, Alexandra; Farsky, Sandra H. P.; Lomonte, Bruno; Angulo Ugalde, Yamileth; Moura Da Silva, Ana M.; Gutiérrez, José María (2001-02)
Stings by Thalassophryne nattereri are responsible for envenomation of fishermen in north-eastern Brazil. Its venom induces prominent local tissue damage, characterized by pain, oedema and necrosis. The pathogenesis of ...
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AuthorGutiérrez, José María (407)Lomonte, Bruno (288)Mata Jiménez, Leonardo (147)Rosero Bixby, Luis (90)Barrantes Montero, Gilbert (81)Alfaro Martínez, Eric J. (80)Calvete Chornet, Juan José (72)Troyo Rodríguez, Adriana (72)Angulo Ugalde, Yamileth (68)Rucavado Romero, Alexandra (67)... View MoreType
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  • Repositorios universitarios

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Repositorio Institucional de la Universidad de Costa Rica. Algunos derechos reservados. Este repositorio funciona con DSpace.