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Myotoxin II from Bothrops asper (Terciopelo) venom is a lysine-49 phospholipase A2 

Francis, Brian; Gutiérrez, José María; Lomonte, Bruno; Kaiser, Ivan I. (1991)
A basic, dimeric myotoxic protein, myotoxin II, purified from Bothrops asper venom has a similar molecular weight and is immunologically cross-reactive with antibodies raised to previously isolated B. asper phospholipases ...
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Neutralization of coral snake Micrurus nigrocinctus venom by a monovalent antivenom 

Gutiérrez, José María; Rojas Céspedes, Gustavo; Pérez, A.; Arguello, I.; Lomonte, Bruno (1991)
The neutralizing ability of a monovalent anti-Micrurus nigrocinctus (coral snake) antivenom produced in Costa Rica was tested against the lethal, myotoxic and phospholipase A2 activities of homologous venom. In addition, ...

Quantitation by enzyme-immunoassay of antibodies against Bothrops myotoxins in four commercially-available antivenoms 

Lomonte, Bruno; Gutiérrez, José María; Rojas Céspedes, Gustavo; Calderón Fuentes, Leonel (1991)
An enzyme-immunoassay (EIA) for the quantitation of antibodies against myotoxins present in the venoms of Bothrops asper (Costa Rica), B. atrox (Colombia) and B. moojeni (Brazil), was developed. This EIA was utilized for ...
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Standardization of assays for testing the neutralizing ability of antivenoms 

Gutiérrez, José María; Rojas Céspedes, Gustavo; Lomonte, Bruno; Gené, José Antonio; Chaves Mora, Fernando; Alvarado, Jorge; Rojas Umaña, Ermila (1990)

Snake Venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus Complex Points to Neurotoxicity as an Adaptive Paedomorphic Trend along Crotalus Dispersal in South America 

Calvete Chornet, Juan José; Sanz, Libia; Cid, Pedro; De La Torre, Pilar; Flores Díaz, Marietta; Dos Santos, María Cristina; Borges, Adolfo; Bremo, Adolfo; Angulo Ugalde, Yamileth; Lomonte, Bruno; Alape Girón, Alberto; Gutiérrez, José María (2010)
We report a comparative venomic and antivenomic characterization of the venoms of newborn and adult specimens of the Central American rattlesnake, Crotalus simus, and of the subspecies cumanensis, durissus, ruruima, and ...

Tissue pathology induced by snake venoms: How to understand a complex pattern of alterations from a systems biology perspective? 

Gutiérrez, José María; Rucavado Romero, Alexandra; Escalante Muñoz, Teresa; Lomonte, Bruno; Angulo Ugalde, Yamileth; Fox, Jay W. (2010-01)
The study of snake venom-induced local tissue pathology has been predominantly based on experimental designs and concepts that view tissue alterations from a dichotomous, homogeneous and reductionist perspective. Experimental ...

Systemic and local myotoxicity induced by snake venom group II phospholipases A2: Comparison between crotoxin, crotoxin B and a Lys49 PLA2 homologue 

Gutiérrez, José María; Ponce Soto, Luis Alberto; Marangoni, Sergio; Lomonte, Bruno (2008-01)
The patterns of myotoxicity induced in mice by crotoxin, crotoxin B and a Lys49 phospholipase A2 (PLA2) homologue were compared. Lys49 PLA2-induced local myotoxicity is reflected by creatine kinase (CK) loss in injected ...

Snake Venomics of the Lesser Antillean Pit Vipers Bothrops caribbaeus and Bothrops lanceolatus: Correlation with Toxicological Activities and Immunoreactivity of a Heterologous Antivenom 

Gutiérrez, José María; Sanz, Libia; Escolano, José; Fernández Ulate, Julián; Lomonte, Bruno; Angulo Ugalde, Yamileth; Rucavado Romero, Alexandra; Warrell, David A.; Calvete Chornet, Juan José (2008-10)
The venom proteomes of the snakes Bothrops caribbaeus and Bothrops lanceolatus, endemic to the Lesser Antillean islands of Saint Lucia and Martinique, respectively, were characterized by reversephase HPLC fractionation, ...
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Snake venomics of the South and Central American Bushmasters. Comparison of the toxin composition of Lachesis muta gathered from proteomic versus transcriptomic analysis 

Sanz, Libia; Escolano, José; Ferretti, Massimo; Biscoglio, Mirtha J.; Rivera, Elena; Crescenti, Ernesto J.; Angulo Ugalde, Yamileth; Lomonte, Bruno; Gutiérrez, José María; Calvete Chornet, Juan José (2008-04-30)
We report the proteomic characterization of the venoms of two closely related pit vipers of the genus Lachesis, L. muta (South American Bushmaster) and L. stenophrys (Central American Bushmaster), and compare the toxin ...
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Trends in Snakebite Envenomation Therapy: Scientific, Technological and Public Health Considerations 

Gutiérrez, José María; Lomonte, Bruno; León Montero, Guillermo; Rucavado Romero, Alexandra; Chaves Mora, Fernando; Angulo Ugalde, Yamileth (2007)
The therapy of snakebite envenomation has been based on the parenteral administration of animal-derived antivenoms. Despite the success of this treatment at reducing the impact of snakebite mortality and morbidity, mostly ...
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Lomonte, Bruno (303)
Gutiérrez, José María (180)Angulo Ugalde, Yamileth (59)Calvete Chornet, Juan José (43)Fernández Ulate, Julián (34)Sanz, Libia (34)Rucavado Romero, Alexandra (22)León Montero, Guillermo (17)Rojas Céspedes, Gustavo (16)Cerdas Fallas, Luis (15)... View MoreTypeartículo científico (288)capítulo de libro (9)contribución a revista (3)otro (1)preprint (1)tesis de doctorado (1)ProcedenceVicerrectoría de Investigación (303)Vicerrectoría de Docencia (48)... View MoreHas File(s)Yes (303)

  • Repositorios universitarios

  • Repositorio del SIBDI-UCR
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Repositorio Institucional de la Universidad de Costa Rica. Algunos derechos reservados. Este repositorio funciona con DSpace.