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dc.creatorJiménez Castro, Lorenaes_ES
dc.creatorHare, Elizabethes_ES
dc.creatorMedina, Rolandoes_ES
dc.creatorNicolini Sánchez, José Humbertoes_ES
dc.creatorMendoza Rodríguez, Ricardoes_ES
dc.creatorOntiveros Sánchez de la Barquera, Jose Alfonsoes_ES
dc.creatorJerez, Álvaroes_ES
dc.creatorMuñoz, Rodrigoes_ES
dc.creatorDassori, Albanaes_ES
dc.creatorEscamilla, Michaeles_ES
dc.creatorRaventós Vorst, Henriettees_ES
dc.date.accessioned2013-11-08T16:03:59Zes_ES
dc.date.available2013-11-08T16:03:59Zes_ES
dc.date.issued2010es_ES
dc.identifier.citationhttp://www.sciencedirect.com/science/article/pii/S0920996410011394es_ES
dc.identifier.issn0920-9964es_ES
dc.identifier.otherESSN: 1573-2509es_ES
dc.identifier.urihttp://hdl.handle.net/10669/8909es_ES
dc.descriptionartículo -- Universidad de Costa Rica. Centro Investigación en Biología Molecular y Celular, 2010. Este documento es privado debido a limitaciones de derechos de autor.es_ES
dc.description.abstractObjectives:The aims of this study were to estimate the frequency and course of substances use disorders in Latino patients with schizophrenia and to ascertain risk factors associated with substance use disorders in this population. Method: We studied 518 subjects with schizophrenia recruited for a genetic study from the Southwest United States, Mexico, and Central America (Costa Rica and Guatemala). Subjects were assessed using structured interviews and a best estimate consensus process. Logistic regression, χ 2 , ttest, Fisher's exact test, and Yates' correction, as appropriate, were performed to assess the sociodemographic variables associated with dual diagnosis. We defined substance use disorder as either alcohol or substance abuse or dependence. Results: Out of 518 patients with schizophrenia, 121 (23.4%) had substance use disorders. Comorbid substance use disorders were associated with male gender, residence in the United States, immigration of Mexican men to the United States, history of depressive syndrome or episode, and being unemployed. The most frequent substance use disorder was alcohol abuse/ dependence, followed by marijuana abuse/dependence, and solvent abuse/dependence. Conclusion: This study provides data suggesting that depressive episode or syndrome, unemployment, male gender, and immigration of Mexican men to the United States were factors associated with substance use disorder comorbidity in schizophrenia. Binary logistic regression showed that country of residence was associated with substance use disorder in schizophrenic patients. The percentage of subjects with comorbid substance use disorders was higher in the Latinos living in the United States compared with subjects living in Central America and Mexico.es_ES
dc.description.sponsorshipUniversidad de Costa Rica. This research was supported by the following grants from the National Institute of Mental Health: MH60881 and MH60875. Dr. Jimenez-Castro was supported by a fellowship of grant D43 TW06152-01 from the National Institute of Mental Health, the National Institute of Drug Abuse and the Fogarty Institute. These institutions had no further role in the study design, in the collection, analysis and interpretation of data, in writing of the report, and in the decision to submit the paper for publicationes_ES
dc.language.isoen_USes_ES
dc.publisherSchizophrenia Research 120 (2010) 87–94es_ES
dc.subjectDrug Abusees_ES
dc.subjectSubstance misusees_ES
dc.subjectAlcoholismes_ES
dc.subjectLatin Americaes_ES
dc.subjectSchizophreniaes_ES
dc.titleSubstance use disorder comorbidity with schizophrenia in families of Mexican and Central American Ancestryes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.identifier.doi10.1016/j.schres.2010.02.1053es_ES
dc.description.procedenceUCR::Investigación::Unidades de Investigación::Ciencias Básicas::Centro de Investigación en Biología Celular y Molecular (CIBCM)es_ES


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