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dc.creatorArguedas Porras, Randall
dc.creatorGómez Argüello, Aarón
dc.creatorBarquero Arroyo, Marco David
dc.creatorChacón Gutiérrez, Danilo
dc.creatorCorrales Chaves, Greivin
dc.creatorHernández, Sonia M.
dc.creatorLeón Montero, Guillermo
dc.date.accessioned2020-11-04T17:26:12Z
dc.date.available2020-11-04T17:26:12Z
dc.date.issued2018
dc.identifier.citationhttps://www.sciencedirect.com/science/article/abs/pii/S0045653518307604?via%3Dihub#!es_ES
dc.identifier.issn0045-6535
dc.identifier.urihttp://hdl.handle.net/10669/81806
dc.description.abstractThe terciopelo (Bothrops asper), is one of the most important venomous snakes in Costa Rica and common on agriculture where insecticides are frequently used for pest control. To assess the exposure to organophosphates on captive B. asper, an experiment using chlorpyrifos and butyrylcholinesterase (BChE), as a biomarker was conducted. In addition to BChE, hematology, aspartate aminotransferase (AST), total proteins (TP) and albumin were measured after exposure. Different concentrations of chlorpyrifos were used in Group A (0.1%) and B (1%), while the Control Group received distilled water; each group was composed of 5 snakes. Values of BChE, AST, TP, and albumin were measured before exposure, and at 6, 12, 24, 196, 360 and 528 h post-exposure. Hematology values were measured after 24 h post-exposure. As result, an important variation between subjects in all groups before exposure was obtained. Moreover, BChE activity showed 37% inhibition of Group A when compared to Control Group at 12 h post-exposure, and a higher inhibition of Group B (97%) related to Control Group, at 6 h postexposure. Recovery of BChE occurred towards 528 h, never reaching initial values. Despite some variation in the rest of parameters used, a marked relative lymphopenia and monocytosis occurred at 24 h, assuming stress as the main cause.es_ES
dc.description.sponsorshipUniversidad de Costa Rica/[741-B7-106]/UCR/Costa Ricaes_ES
dc.language.isoen_USes_ES
dc.sourceChemosphere, vol.205, pp.209-214es_ES
dc.subjectPesticideses_ES
dc.subjectAcetylcholinesterase inhibitorses_ES
dc.subjectBothrops asperes_ES
dc.subjectOrganophosphateses_ES
dc.titleEffect of exposition to chlorpyrifos upon plasmatic cholinesterases, hematology and blood biochemistry values in Bothrops asper (Serpentes: Viperidae)es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.identifier.doi10.1016/j.chemosphere.2018.04.111
dc.description.procedenceUCR::Vicerrectoría de Docencia::Salud::Facultad de Microbiologíaes_ES
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es_ES
dc.description.procedenceUCR::Vicerrectoría de Docencia::Ciencias Básicas::Facultad de Ciencias::Escuela de Biologíaes_ES
dc.description.procedenceUCR::Sedes Regionales::Sede del Caribe::Recinto Limónes_ES
dc.identifier.codproyecto741-B7-106


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