Universidad de Costa Rica
  • Sobre Kérwá
  • Acceso Abierto
  • Cómo Depositar
  • Políticas
  • Contacto
    • español
    • English
  • English 
    • español
    • English
  • Login
View Item 
  •   Kérwá Home
  • Investigación
  • Ciencias básicas
  • Química
  • View Item
  •   Kérwá Home
  • Investigación
  • Ciencias básicas
  • Química
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Superoxide dismutase based biosensor for the electrochemical determination of epinephrine

Artículo científico
View/Open
superoxide-dismutase-based-biosensor-for-the-electrochemical-determination-of-epinephrine.pdf (458.0Kb)
Date
2018
Author
Barquero Quirós, Mirian
Cunha Silva, Hugo
Arcos Martínez, María Julia
Metadata
Show full item record
Abstract
New amperometric biosensor for epinephrine was developed, using a screen printed carbon electrode with tetrathiafulvalene (5% v/w) incorporated into carbon ink (SPCTTFE). Electrodic surface was modified with nanoparticles of Au, Pt, Pd and Rh deposited on SPCTTFE by cyclic voltammetry. When using Pd nanoparticles, slope of EPI calibration curves was higher than the performed with the others NPs. The electrodeposited nanoparticles were evaluated with atomic force microscopy and electrochemical impedance spectroscopy was used to characterize electrode process. The developed superoxide dismutase-based biosensor was characterized by: limit of detection of 5.3 × 10-6 M (n=4), limit of quantification of 17.5 × 10-6 M (n=4), reproducibility with RSD of 2.8% (n=5), repeatability with RSD of 0.97% (n=3), accuracy was 102.8% with RSD of 4.3% (n=5). Linearity was obtained from 17.0 × 10-5 M to 8.59 × 10-4M. Interference study performed adding ascorbic acid and uric acid exhibits that the peak potential of both species are higher than the chosen for epinephrine analysis. Therefore developed biosensor and described in this paper, has been successfully applied to the determination of epinephrine in human gamma globulin and pharmaceutical samples. Developed biosensor offers easy assembly, excellent linearity and good performance parameters.
URI
http://hdl.handle.net/10669/80689
https://www.tsijournals.com/abstract/superoxide-dismutase-based-biosensor-for-the-electrochemical-determination-of-epinephrine-13841.html
Collections
  • Química [137]



  • Repositorios universitarios

  • Repositorio del SIBDI-UCR
  • Biblioteca Digital del CIICLA
  • Repositorio Documental Rafael Obregón Loría (CIHAC)
  • Biblioteca Digital Carlos Melendez (CIHAC)
  • Repositorio de Fotografías
  • Colección de videos de UPA-VAS
  • Sitios recomendados

  • Buscador regional de LA Referencia
  • Buscador del Open ROAR
  • Scientific Electronic Library Online (SciELO)
  • Directory of Open Access Journals (DOAJ)
  • Redalyc
  • Redes sociales

  • facebook.com/repositoriokerwa
  • @Ciencia_UCR
  • Sobre Kérwá
  • Acceso Abierto
  • Cómo depositar
  • Políticas
Contact Us | Send Feedback
Repositorio Institucional de la Universidad de Costa Rica. Algunos derechos reservados. Este repositorio funciona con DSpace.
Universidad de Costa Rica
 

 

Browse

All of KérwáCommunities & CollectionsTitlesAuthorsSubjectsProcedenceTypeThis CollectionTitlesAuthorsSubjectsProcedenceType

My Account

LoginRegister

  • Repositorios universitarios

  • Repositorio del SIBDI-UCR
  • Biblioteca Digital del CIICLA
  • Repositorio Documental Rafael Obregón Loría (CIHAC)
  • Biblioteca Digital Carlos Melendez (CIHAC)
  • Repositorio de Fotografías
  • Colección de videos de UPA-VAS
  • Sitios recomendados

  • Buscador regional de LA Referencia
  • Buscador del Open ROAR
  • Scientific Electronic Library Online (SciELO)
  • Directory of Open Access Journals (DOAJ)
  • Redalyc
  • Redes sociales

  • facebook.com/repositoriokerwa
  • @Ciencia_UCR
  • Sobre Kérwá
  • Acceso Abierto
  • Cómo depositar
  • Políticas
Contact Us | Send Feedback
Repositorio Institucional de la Universidad de Costa Rica. Algunos derechos reservados. Este repositorio funciona con DSpace.
Universidad de Costa Rica