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dc.creatorMurray, Christopher M.
dc.creatorMerchant, Mark
dc.creatorEaster, Michael
dc.creatorPadilla, Sergio
dc.creatorGarrigós, Davinia B.
dc.creatorSasa Marín, Mahmood
dc.creatorGuyer, Craig
dc.date.accessioned2019-05-14T14:08:01Z
dc.date.available2019-05-14T14:08:01Z
dc.date.issued2017-08
dc.identifier.citationhttps://www.sciencedirect.com/science/article/pii/S004565351730543X#!es_ES
dc.identifier.issn0045-6535
dc.identifier.urihttp://hdl.handle.net/10669/77109
dc.description.abstractEndocrine-disrupting contaminants (EDC's) are well known to alter sexual differentiation among vertebrates via estrogenic effects during development, particularly in organisms characterized by temperature-dependent sex determination. However, substances producing androgenic effects typically lack potency when tested in laboratory settings and are virtually unstudied in field settings. Here, we assay levels of a synthetic androgen, 17a-methyltestosterone (MT), in a heavily male-biased population of American crocodiles in the Tempisque River Basin of Costa Rica based on the recent hypothesis that this chemical is an EDC in developing crocodilian embryos. The presence of MT was documented in all fieldcollected samples of egg yolk and in plasma of all age classes in among population of crocodiles. Hatchlings exhibited higher plasma MT concentrations (102.1 ± 82.8 ng/mL) than juveniles (33.8 ± 51.5) and adults (25.9 ± 20.8 ng/mL). Among populations, crocodiles captured in the Tempisque River (62.9 ± 73.7 ng/mL) were higher in MT concentration than those from Tarcoles (13.3 ± 11.4 ng/mL) and negative controls (0.001 ± 0.0002 ng/mL). A mechanism for the bio-transport of MT and its subsequent effects is proposed.es_ES
dc.description.sponsorshipUniversidad de Costa Rica/[741-B5-270]/UCR/Costa Ricaes_ES
dc.description.sponsorshipOrganization for Tropical Studies/[OTS 507]/OTS/Costa Ricaes_ES
dc.language.isoen_USes_ES
dc.sourceChemosphere, vol.180, pp. 125-129es_ES
dc.subjectMethyltestosteronees_ES
dc.subjectEndocrine disrupting contaminantses_ES
dc.subjectEnvironmental androgenes_ES
dc.subjectCrocodyluses_ES
dc.subject597.987 286 Crocodilia (Cocodrilos)es_ES
dc.titleDetection of a synthetic sex steroid in the American crocodile (Crocodylus acutus): Evidence for a novel environmental androgenes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.date.updated2019-05-09T14:15:42Z
dc.identifier.doi10.1016/j.chemosphere.2017.04.020
dc.description.procedenceUCR::Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es_ES
dc.description.procedenceUCR::Docencia::Salud::Facultad de Microbiologíaes_ES
dc.identifier.codproyecto741-B5-270


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