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Diketopiperazines from Costa Rican endolichenic fungus Colpoma sp. CR1465A
dc.creator | Lee, Seulah | |
dc.creator | Tamayo Castillo, Giselle | |
dc.creator | Pang, Changhyun | |
dc.creator | Clardy, Jon | |
dc.creator | Cao, Shugeng | |
dc.creator | Kim, Ki Hyun | |
dc.date.accessioned | 2018-04-09T16:12:47Z | |
dc.date.available | 2018-04-09T16:12:47Z | |
dc.date.issued | 2016-05-15 | |
dc.identifier.citation | https://www.sciencedirect.com/science/article/pii/S0960894X16303468?via%3Dihub | |
dc.identifier.issn | 0960-894X | |
dc.identifier.uri | https://hdl.handle.net/10669/74427 | |
dc.description.abstract | Three new diketopiperazines (1–3), cyclo(l-Pro-d-trans-Hyp) (1), cyclo(l-Pro-d-Glu) (2), and cyclo(d-Pro-d-Glu) (3) and five known diketopiperazines (4–8) were isolated from the endolichenic fungus Colpoma sp. CR1465A identified from the Costa Rican plant Henriettea tuberculosa (Melatomataceae). The structures of the new compounds 1–3 were elucidated using a combination of extensive spectroscopic analyses, including 2D NMR and HR-MS, and their absolute configurations were determined by a combination of NOESY analysis and Marfey’s method. Cyclo(l-Pro-d-allo-Thr) (4) was recently isolated from a South China Sea marine sponge Callyspongia sp., but its NMR spectroscopic data were not reported, and cyclo(l-Pro-l-Asp) (5) was previously reported but only as a synthetic product. The NMR data assignments of compounds 4 and 5 are reported for the first time. All of the isolated compounds were tested for antifungal and antimicrobial properties. | es_ES |
dc.description.sponsorship | SEOK CHUN Research Fund-Sungkyunkwan University/[]/SKKU/Corea | es_ES |
dc.language.iso | en_US | es_ES |
dc.source | Bioorganic & Medicinal Chemistry Letters, Vol. 26(10), pp.2438-2441 | es_ES |
dc.subject | Colpoma sp. | es_ES |
dc.subject | Henriettea tuberculosa | es_ES |
dc.subject | Diketopiperazines | es_ES |
dc.subject | Marfey’s method | es_ES |
dc.title | Diketopiperazines from Costa Rican endolichenic fungus Colpoma sp. CR1465A | es_ES |
dc.type | artículo original | |
dc.identifier.doi | 10.1016/j.bmcl.2016.03.115 | |
dc.description.procedence | UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Básicas::Centro de Investigaciones en Productos Naturales (CIPRONA) | es_ES |
dc.identifier.pmid | 27080179 |
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Biología [1641]