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dc.creatorMasís Calvo, Marianela
dc.creatorSequeira Cordero, Andrey
dc.creatorMora Gallegos, Andrea
dc.creatorFornaguera Trías, Jaime
dc.date.accessioned2018-01-23T21:07:16Z
dc.date.available2018-01-23T21:07:16Z
dc.date.issued2013
dc.identifier.citationhttp://www.sciencedirect.com/science/article/pii/S0031938413001753?via%3Dihubes_ES
dc.identifier.issn0031-9384
dc.identifier.urihttp://hdl.handle.net/10669/73977
dc.description.abstractMaternal care represents a major constituent of early life environment and has the potential to modulate critical neurobehavioral responses to stress. The aim of the present study was to determine the effects of naturally occurring variations in maternal care on behavioral and neurochemical responses of juvenile Sprague–Dawley rats. A group of dams were classified based on their licking behavior in high and low licking-grooming mothers. Afterwards, the male offspring was tested in a series of behavioral tests: open field test (OFT), elevated plus maze (EPM) and forced swimming test (FST). Additionally, monoamine concentrations were determined postmortem in three brain regions: hippocampus, ventral striatum and prefrontal cortex. Our findings suggest that maternal care variations have an effect on several anxiety-related behaviors in OFT and EPM but not in depression-like behaviors in FST. Such behavioral differences could be related to an increased DOPAC concentration and 5-HT turnover in prefrontal cortex. These evidences suggest that natural variations in maternal care modified some behavioral and neurochemical parameters related with anxiety and stress in this straines_ES
dc.description.sponsorshipUniversidad de Costa Rica/[422-A9-607]/UCR/Costa Ricaes_ES
dc.language.isoen_USes_ES
dc.sourcePhysiology & Behavior, Vol. 118, pp. 212–217es_ES
dc.subjectMaternal carees_ES
dc.subjectAnxietyes_ES
dc.subjectStress responsees_ES
dc.subjectGrooming behaviores_ES
dc.subjectMonoamineses_ES
dc.subjectSprague–Dawleyes_ES
dc.titleBehavioral and neurochemical characterization of maternal care effects on juvenile Sprague–Dawley ratses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.identifier.doi10.1016/j.physbeh.2013.05.033
dc.description.procedenceUCR::Docencia::Salud::Facultad de Medicina::Escuela de Medicinaes_ES
dc.description.procedenceUCR::Investigación::Unidades de Investigación::Ciencias de la Salud::Centro de Investigación en Neurociencias (CIN)es_ES
dc.description.procedenceUCR::Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA)es_ES
dc.identifier.codproyecto422-A9-607


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