Show simple item record

dc.creatorParra Villalobos, Jonathan
dc.creatorGarcía Barrantes, Pedro M.
dc.creatorRodriguez Rodriguez, Gerardo
dc.date.accessioned2017-12-21T16:20:05Z
dc.date.available2017-12-21T16:20:05Z
dc.date.issued2016
dc.identifier.citationhttp://jppres.com/jppres/characterization-of-matricaria-recutita-tinctures/es_ES
dc.identifier.issn0719-4250
dc.identifier.urihttp://hdl.handle.net/10669/73725
dc.description.abstractContext: The pharmacological activity of medicinal products containing plant materials depends on their specific components. However, these components are not characterized in their entirety in all cases. Therefore, manufacturing processes must be duly characterized and validated. Aims: To characterize a chamomile (Matricaria recutita) tincture through chemometric analysis of chromatographic data in order to establish quality parameters for its production. Methods: Various chamomile tinctures were manufactured and the precision and robustness of the production process for each was verified. The physicochemical properties of the tinctures were characterized and their chromatographic digital fingerprints analysed through chemometric methods. Results: A good correlation between the physicochemical characterization and the chromatographic analysis was demonstrated. The preparation methodology was proved to be repeatable as long as the source of the plant material is not altered. Conclusions: The principal component multivariate analysis of chromatograms was a helpful and simple tool for the characterization and traceability of the production method.es_ES
dc.description.sponsorshipConsejo Nacional de Rectores/[CNR-351-08]/CONARE/Costa Ricaes_ES
dc.language.isoen_USes_ES
dc.sourceJournal of Pharmacy & Pharmacognosy Research, vol. 4 (1), pp.18-24es_ES
dc.subjectLiquid chromatographyes_ES
dc.subjectMatricaria recutitaes_ES
dc.subjectPrincipal components analysises_ES
dc.subjectTincturees_ES
dc.titlePhysicochemical and chromatographic method of characterization of Matricaria recutita tinctureses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones Farmacéuticas (INIFAR)es_ES


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record