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dc.creatorSoto Garita, Claudio
dc.creatorSomogyi Pérez, Teresa
dc.creatorVicente Santos, Amanda
dc.creatorCorrales Aguilar, Eugenia
dc.date.accessioned2017-07-18T19:21:11Z
dc.date.available2017-07-18T19:21:11Z
dc.date.issued2016-07
dc.identifier.citationhttp://www.ajtmh.org/content/journals/10.4269/ajtmh.15-0835es_ES
dc.identifier.issn0002-9637
dc.identifier.urihttp://hdl.handle.net/10669/30373
dc.description.abstractDengue virus (DENV) (Flavivirus, Flaviviridae) is a reemerging arthropod-borne virus with a worldwide circulation, transmitted mainly by Aedes aegypti and Aedes albopictus mosquitoes. Since the first detection of its main transmitting vector in 1992 and the invasion of DENV-1 in 1993, Costa Rica has faced dengue outbreaks yearly. In 2007 and 2013, Costa Rica experienced two of the largest outbreaks in terms of total and severe cases. To provide genetic information about the etiologic agents producing these outbreaks, we conducted phylogenetic analysis of viruses isolated from human samples. A total of 23 DENV-1 and DENV-2 sequences were characterized. These analyses signaled that DENV-1 genotype V and DENV-2 American/Asian genotype were circulating in those outbreaks. Our results suggest that the 2007 and 2013 outbreak viral strains of DENV-1 and DENV-2 originated from nearby countries and underwent in situ microevolution.es_ES
dc.language.isoen_USes_ES
dc.sourceThe American Journal of Tropical Medicine and Hygiene, Volume 95, Issue 1. 2016es_ES
dc.subjectViruses_ES
dc.subjectAedes aegypties_ES
dc.subjectAedes albopictuses_ES
dc.subjectDenguees_ES
dc.titleMolecular Characterization of Two Major Dengue Outbreaks in Costa Ricaes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.identifier.doihttps://doi.org/10.4269/ajtmh.15-0835
dc.description.procedenceUCR::Investigación::Unidades de Investigación::Ciencias de la Salud::Centro de Investigación en Enfermedades Tropicales (CIET)es_ES
dc.description.procedenceUCR::Docencia::Salud::Facultad de Microbiologíaes_ES


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