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dc.creatorGutiérrez, José María
dc.date.accessioned2017-06-16T20:15:50Z
dc.date.available2017-06-16T20:15:50Z
dc.date.issued2014-09-01
dc.identifier.citationhttps://academic.oup.com/trstmh/article-lookup/doi/10.1093/trstmh/tru102es_ES
dc.identifier.issn1878-3503
dc.identifier.urihttp://hdl.handle.net/10669/30125
dc.description.abstractSnakebite envenoming constitutes an important public health problem in Latin America and some countries of the Caribbean. The advances and pending tasks in the study and control of this neglected tropical disease in this region are reviewed in the light of a roadmap proposed in 2006. Significant progress has been achieved in the study of snake venoms, particularly regarding venom proteomics, i.e.‘venomics’, and the analysis of the mechanism of action of toxins. Likewise, a deeper understanding has been gained in the preclinical efficacy of antivenoms produced in the region. In contrast, despite advances made in the study of clinical manifestations of envenomings and safety and efficacy of antivenoms at the clinical level, much remains to be done in this subject. Improvements have occurred in antivenom manufacturing technologies and availability, although there are still countries where there is insufficient supply of antivenoms, or where manufacture has to be improved. In spite of considerable efforts in some countries in prevention, accessibility to treatment, and training of health staff in the management of envenomings, important challenges remain for the region as a whole, with the long term goal of reducing the impact of this disease in terms of personal and social suffering.es_ES
dc.description.sponsorshipUniversidad de Costa Rica//UCR/Costa Ricaes_ES
dc.language.isoen_USes_ES
dc.sourceTransactions of The Royal Society of Tropical Medicine and Hygiene; Volumen 108, Número 9. 2014es_ES
dc.subjectAntivenomses_ES
dc.subjectCaribbeanes_ES
dc.subjectEnvenominges_ES
dc.subjectLatin Americaes_ES
dc.subjectSnakebitees_ES
dc.subjectVenomses_ES
dc.subjectSnake venomes_ES
dc.titleReducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges aheades_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.identifier.doi10.1093/trstmh/tru102
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es_ES
dc.identifier.pmid25096295


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