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dc.creatorBorkow, Gadi
dc.creatorGutiérrez, José María
dc.creatorOvadia, Michael
dc.date.accessioned2016-11-11T16:39:59Z
dc.date.available2016-11-11T16:39:59Z
dc.date.issued1995-10
dc.identifier.citationhttp://www.sciencedirect.com/science/article/pii/004101019500078Zes_ES
dc.identifier.issn0041-0101
dc.identifier.urihttp://hdl.handle.net/10669/29242
dc.description.abstractIncubation of BaH1, the main hemorrhagic toxin purified from the venom of Bothrops asper, with endothelial cells caused the appearance of spaces among the cells. This effect became more noticeable with increasing hemorrhagin concentration and longer incubation time. Later, the cells became rounded and detached from the substrate into the medium. Augmentation of Trypan blue did not stain the detached cells, indicating their viability. Moreover, after washing the floating cells from the toxin they could be recultivated: they again spread on the substrate and proliferated, demonstrating that BaHl is not directly cytotoxic to the endothelial cellses_ES
dc.language.isoen_USes_ES
dc.sourceToxicon Volumen 33, Número 10. 1995es_ES
dc.subjectAnimalses_ES
dc.subjectBothropses_ES
dc.subjectCattlees_ES
dc.subjectCrotalid Venomses_ES
dc.subjectEndopeptidaseses_ES
dc.subjectEndotheliumes_ES
dc.subjectEndothelium, Vasculares_ES
dc.subjectIn Vitro Techniqueses_ES
dc.titleIn vitro activity of BaH1, the main hemorrhagic toxin of Bothrops asper snake venom on bovine endothelial cellses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.identifier.doi10.1016/0041-0101(95)00078-Z
dc.description.procedenceUCR::Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es_ES


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