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dc.creatorLomonte, Brunoes_ES
dc.creatorGené, José Antonioes_ES
dc.creatorGutiérrez, José Maríaes_ES
dc.creatorCerdas Fallas, Luises_ES
dc.date.accessioned2016-11-02T22:45:06Zes_ES
dc.date.available2016-11-02T22:45:06Zes_ES
dc.date.issued1983es_ES
dc.identifier.citationhttp://www.sciencedirect.com/science/article/pii/0041010183900946es_ES
dc.identifier.issn0041-0101es_ES
dc.identifier.urihttp://hdl.handle.net/10669/29136es_ES
dc.descriptionEsta investigación fue financiada por la Vicerrectoría de Investigación de la Universidad de Costa Rica, Proyecto No 02-07 10-67es_ES
dc.description.abstractVenoms from adult and newborn Central American rattlesnakes (Crotalus durissus durissus) were compared for lethal, proteolytic, hemorrhagic, myonecrotic, edematigenous and in vitro hemolytic activities. Electrophoretic and immunoelectrophoretic patterns showed some differences between these venoms. Venom from newborn snakes was devoid of hemorrhagic and edematigenous activities, whereas the venom from adult specimens induced these effects. On the other hand, newborn snake venom showed higher lethality and indirect hemolytic activity, and lower proteolytic activity, than venom from adult specimens. Both types of venoms induced only slight myonecrosis in mice, as judged by histological observation. The ED50 of an antivenom, in terms of absolute weight neutralized per ml of serum, was lower for the newborn specimens venom than for adult's venom, however, for each venom the number of LD50 neutralized was similar.es_ES
dc.description.sponsorshipUniversidad de Costa Rica, Vicerrectoría de Investigaciónes_ES
dc.language.isoen_USes_ES
dc.sourceToxicon 21(3):379-384, 1983es_ES
dc.subjectSerpienteses_ES
dc.subjectVeneno de serpientees_ES
dc.titleEstudio comparativo de los venenos de serpiente Cascabel (Crotalus durissus durissus) de ejemplares adultos y recien nacidoses_ES
dc.title.alternativeComparative study of venoms of newborn and adult rattlesnakes (Crotalus durissus durissus)es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.identifier.doi10.1016/0041-0101(83)90094-6es_ES
dc.description.procedenceUCR::Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es_ES


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