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El problema de los efectos hemorrágico y mionecrótico por mordeduras de serpiente en el continente Americano
(1980)
Los efectos locales que aparecen como consecuencia de la mordedura de serpientes constituyen un problema de salud importante en las Américas. Sin embargo, la eficacia del suero antiofídico que se usa parece ser escasa, ...
Efectos proteolitico, hemorragico y mionecrotico de los venenos de serpientes costarricenses de los generos Bothrops, Crotalus y Lachesis
(1980)
We studied the proteolytic, hemorrhagic and myonecrotic activities of ten Costa Rican species of snakes from the family Viperidae. All of them showed these three activities but we did not observe any correlation between ...
Cariotipos de las principales serpientes coral (Elapidae: Micrurus) de Costa Rica
(1979)
Se describen los cariotipos de las tres especies de serpientes de coral (Elapidae: Micrurus) más abundantes en Costa Rica: M. nigrocinctus, M. alleni y M. mipartitus. M. nigrocinctus presenta dos poblaciones cariotípicas ...
Neutralization of proteolytic and hemorrhagic activities of Costa Rican snake venoms by a polyvalent antivenom
(1985)
The polyvalent antivenom produced at the Instituto Clodomiro Picado, Costa Rica, was tested for its capacity to neutralize proteolytic and hemorrhagic activities of ten Costa Rican crotaline venoms. In experiments with ...
Cariotipos de diez especies de serpientes costarricenses de la familia Viperidae
(1979)
All the karyotypes of ten snake species of the family Viperidae from Costa Rica have a diploid number of 36 chromosomes, 16 macro- and 20 microchromosomes; females show an heteromorphism in the fourth pair. The karyological ...
Quantitation of myonecrosis induced by myotoxin a from prairie rattlesnake (Crotalus viridis viridis) venom
(1982)
Using a pure myotoxin (myotoxin a) isolated from prairie rattlesnake Crotalus viridis viridis) venom, a comparison between two methods for quantitating myonecrosis in mice was made. Measurement of creatine kinase (CK) ...
Isolation of a myotoxin from Bothrops asper venom: Partial characterization and action on skeletal muscle
(1984)
A myotoxic phospholipase has been isolated from Bothrops asper venom by ion-exchange chromatography on CM-Sephadex followed by gel filtration on Sephadex G-75. The toxin is a basic polypeptide with an estimated molecular ...
Pharmacological activities of a toxic phospholipase A isolated from the venom of the snake Bothrops asper
(1986)
A toxic phospholipase A was isolated from the venom of Bothrops asper. It induced skeletal muscle damage, anticoagulant effects and edema in the foot pad. The toxin had an intravenous LD50 of 95 micrograms/16-18 g mouse ...
Mecanismo de acción de miotoxinas aisladas de venenos de serpientes
(1984)
Biochemically and pharmacologically, myotoxins isolated from snake venoms can be placed in four main groups: myolaxic phospholipases A, low molecular weight basic toxins, cardiotoxins, and hemorrhagic myotoxins. The myotoxic ...
Comparative study of the edema-forming activity of Costa Rican snake venoms and its neutralization by a polyvalent antivenom
(1986)
The edema-forming activity of eight Costa Rican crotaline snake venoms and its neutralization by a polyvalent antivenom were studied using the mouse footpad test. All of the venoms induced edema, the highest activity being ...