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Genetic diversity in Oryza glumaepatula wild rice populations in Costa Rica and possible gene flow from O. sativa
(2016-04-07)
Wild crop relatives are an important source of genetic diversity for crop improvement. Diversity estimates are generally lacking for many wild crop relatives. The objective of the present study was to analyze how genetic ...
Genetic contributions to circadian activity rhythm and sleep pattern phenotypes in pedigrees segregating for severe bipolar disorder
(2016-02-09)
Abnormalities in sleep and circadian rhythms are central features of bipolar disorder (BP), often persisting between episodes. We report here, to our knowledge, the first systematic analysis of circadian rhythm activity ...
Salivary gland morphology, tissue tropism and the progression of tospovirus infection in Frankliniella occidentalis
(2016)
Tomato spotted wilt virus (TSWV) is transmitted by thrips in a propagative manner; however, progression of virus infection in the insect is not fully understood. The goal of this work was to study the morphology and infection ...
Sobre el genoma humano, la medicina personalizada y el sistema de seguridad social
(2016)
La promesa del proyecto del genoma humano (PGH) fue que iba a transformar radicalmente la práctica médica. Cambiaría el paradigma de “diagnóstico y tratamiento” por el de “predicción de riesgo y prevención”. Hace más de ...
Characterization of Expression Quantitative Trait Loci in Pedigrees from Colombia and Costa Rica Ascertained for Bipolar Disorder
(2016-05-13)
The observation that variants regulating gene expression (expression quantitative trait loci, eQTL) are at a high frequency among SNPs associated with complex traits has made the genome-wide characterization of gene ...
Phylogenetic reassessment of Specklinia and its allied genera in the pleurothallidinae (Orchidaceae)
(2016)
The phylogenetic relationships within Specklinia (Pleurothallidinae; Orchidaceae) and related genera are re-evaluated using Bayesian analyses of nrITS and chloroplast matK sequence data of a wide sampling of species. ...
Characterization of a Bacillus thuringiensis strain collection isolated from diverse Costa Rican natural ecosystems
Como los ecosistemas naturales de Costa Rica figuran entre los más diversos del mundo, se propuso aislar la bacteria entomopatógena Bacillus thuringiensis (Bt) con el fin de conformar una colección de cepas y caracterizarlas ...
Hallazgos fenotípicos por imágenes con Tomografía Dental Volumétrica (TDV) en amelogénesis imperfecta
Use of Dental Volumetric Tomography for Dental Phenotyping In Amelogenesis Imperfecta
(2016)
Amelogénesis imperfecta (AI) se describe como un conjunto de defectos mendelianos en la biomineralización del esmalte dental, los cuales son severos en la mayoría de los casos al presentar anormalidades tales como un grosor ...
A time- and cost-effective strategy to sequence mammalian Y Chromosomes: an application to the de novo assembly of gorilla Y
(2016-02)
The mammalian Y Chromosome sequence, critical for studying male fertility and dispersal, is enriched in repeats and palindromes, and thus, is the most difficult component of the genome to assemble. Previously, expensive ...
