Listar Biología por autor "6a9bac5f-130f-4977-8ddf-ab97fcafacc4"
Mostrando ítems 1-20 de 22
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Body distribution of Bothrops asper (terciopelo) snake venom myotoxin and its relationship to pathological changes
Moreno Robles, Edgardo; Gutiérrez, José María (1988)The distribution of 125I-labelled Bothrops asper myotoxin following i.m. and i.v. injections was studied in mice. After i.m. administration the toxin was concentrated in the injected gastrocnemius muscle, with relatively ... -
Cariotipos de diez especies de serpientes costarricenses de la familia Viperidae
Gutiérrez, José María; Taylor, Richard T.; Bolaños Herrera, Róger (1979)All the karyotypes of ten snake species of the family Viperidae from Costa Rica have a diploid number of 36 chromosomes, 16 macro- and 20 microchromosomes; females show an heteromorphism in the fourth pair. The karyological ... -
Cariotipos de las principales serpientes coral (Elapidae: Micrurus) de Costa Rica
Gutiérrez, José María; Bolaños Herrera, Róger (1979)Se describen los cariotipos de las tres especies de serpientes de coral (Elapidae: Micrurus) más abundantes en Costa Rica: M. nigrocinctus, M. alleni y M. mipartitus. M. nigrocinctus presenta dos poblaciones cariotípicas ... -
Clodomiro Picado y sus años de formación científica
Monge Nájera, Julián; Gutiérrez, José María (1989)Se analizan una serie de factores socioeconómicos, políticas y culturales que jugaron un papel importante en los años de formación del científica costarricense Clodomiro Picado Twight. E! desarrollo político y cultural de ... -
Comparative study of the edema-forming activity of Costa Rican snake venoms and its neutralization by a polyvalent antivenom
Gutiérrez, José María; Rojas Céspedes, Gustavo; Lomonte, Bruno; Gené, José Antonio; Cerdas Fallas, Luis (1986)The edema-forming activity of eight Costa Rican crotaline snake venoms and its neutralization by a polyvalent antivenom were studied using the mouse footpad test. All of the venoms induced edema, the highest activity being ... -
Costa rican international cooperative biodiversity group: using insects and other arthropods in biodiversity prospecting
Sittenfeld Appel, Ana; Tamayo Castillo, Giselle; Nielsen Muñoz, Vanessa; Jiménez Ardón, Allan Miguel; Hurtado Hernández, Priscilla; Chinchilla Carmona, Misael; Guerrero Bermúdez, Olga Marta; Mora, María Auxiliadora; Rojas, Miguel; Blanco, Roger; Alvarado, Eugenio; Gutiérrez, José María; Janzen, Daniel Hunt (Pharmaceutical Biology 37(Supplement):55–68. 1999, 1999)This paper describes the Costa Rican International Collaborative Biodiversity Group (ICBG), which was designed to introduce insects and other arthropods as a source of pharmaceutical compounds, and to generate knowledge ... -
Efectos proteolitico, hemorragico y mionecrotico de los venenos de serpientes costarricenses de los generos Bothrops, Crotalus y Lachesis
Gutiérrez, José María; Chaves Mora, Fernando (1980)We studied the proteolytic, hemorrhagic and myonecrotic activities of ten Costa Rican species of snakes from the family Viperidae. All of them showed these three activities but we did not observe any correlation between ... -
Estudio comparativo de los venenos de serpiente Cascabel (Crotalus durissus durissus) de ejemplares adultos y recien nacidos
Lomonte, Bruno; Gené, José Antonio; Gutiérrez, José María; Cerdas Fallas, Luis (1983)Venoms from adult and newborn Central American rattlesnakes (Crotalus durissus durissus) were compared for lethal, proteolytic, hemorrhagic, myonecrotic, edematigenous and in vitro hemolytic activities. Electrophoretic and ... -
Estudio comparativo de venenos de ejemplares recien nacidos y adultos de Bothrops asper
Gutiérrez, José María; Chaves Mora, Fernando; Bolaños Herrera, Róger (1980)Se estudiaron comparativamente los venenos de ejemplares recién nacidas (menos de un mes de edad) y adultas de Bothrops asper de dos regiones costarricenses: San Carlos en la vertiente atlántica y Puriscal en la pacífica. ... -
Estudios cariológicos de cinco especies de serpientes costarricenses de la familia colubridae
Solórzano López, Alejandro; Gutiérrez, José María; Cerdas Fallas, Luis (1984)The karyotypes of five species of colubrid snakes from Costa Rica are as follows: Imuntodes cenchao and Drymobius margaritiferus have a diploid number of 36, with 16 macro- and 20 microchromosomes. The fourth pair is ... -
Inflammatory infiltrate in skeletal muscle injected with Bothrops asper venom
Gutiérrez, José María; Chaves Mora, Fernando; Cerdas Fallas, Luis (1986)The time-course and composition of inflammatory infiltrate in mouse gastrocnemius injected with Bothrops asper venom was studied. The venom induced myonecrosis, and a prominent decrease in muscle levels of creatine kinase ... -
Isolation of a myotoxin from Bothrops asper venom: Partial characterization and action on skeletal muscle
Ownby, Charlotte L.; Odell, George V.; Gutiérrez, José María (1984)A myotoxic phospholipase has been isolated from Bothrops asper venom by ion-exchange chromatography on CM-Sephadex followed by gel filtration on Sephadex G-75. The toxin is a basic polypeptide with an estimated molecular ... -
Karyotype of the yellow-bellied sea snake, Pelamis platurus
Gutiérrez, José María; Bolaños Herrera, Róger (1980)In this paper we describe the karyotype of the yellow-bellied sea snake, Pelamis platurus from Costa Rica. The diploid number is 38 chromosomes, with 20 macrochromosomes and 18 microchromosomes. The pairs 1 and 2 are ... -
Mecanismo de acción de miotoxinas aisladas de venenos de serpientes
Cerdas Fallas, Luis; Gutiérrez, José María (1984)Biochemically and pharmacologically, myotoxins isolated from snake venoms can be placed in four main groups: myolaxic phospholipases A, low molecular weight basic toxins, cardiotoxins, and hemorrhagic myotoxins. The myotoxic ... -
Mionecrosis, hemorragia y edema inducidos por el veneno de Bothrops asper en ratón blanco
Gutiérrez, José María; Arroyo Gutiérrez, Olga; Bolaños Herrera, Róger (1980)Pathogenesis of the myonecrotic, hemorrhagic and edema-forming effects in white mice inoculated with Bothrops asper venom was studied at different time intervals by means of light microscopy, determination of serum levels ... -
Neutralization of proteolytic and hemorrhagic activities of Costa Rican snake venoms by a polyvalent antivenom
Gutiérrez, José María; Gené, José Antonio; Rojas Céspedes, Gustavo; Cerdas Fallas, Luis (1985)The polyvalent antivenom produced at the Instituto Clodomiro Picado, Costa Rica, was tested for its capacity to neutralize proteolytic and hemorrhagic activities of ten Costa Rican crotaline venoms. In experiments with ... -
Pathogenesis of myonecrosis induced by crude venom and a myotoxin of Bothrops asper.
Ownby, Charlotte L.; Odell, George V.; Gutiérrez, José María (1984)The pathogenesis of skeletal muscle necrosis induced by crude Bothrops asper venom and isolated myotoxic phospholipase was studied using light and electron microscopy. White mice were injected intramuscularly with a dose ... -
Pharmacological activities of a toxic phospholipase A isolated from the venom of the snake Bothrops asper
Gutiérrez, José María; Lomonte, Bruno; Chaves Mora, Fernando; Moreno Robles, Edgardo; Cerdas Fallas, Luis (1986)A toxic phospholipase A was isolated from the venom of Bothrops asper. It induced skeletal muscle damage, anticoagulant effects and edema in the foot pad. The toxin had an intravenous LD50 of 95 micrograms/16-18 g mouse ... -
Polimorfismo cromosómico intraespecífico en la serpiente de coral Micrurus nigrocinctus (Ophidia: Elapidae)
Gutiérrez, José María; Bolaños Herrera, Róger (1981)En un estudio cito genético de 59 ejemplares de la serpiente de coral Micrurus nigrocinctus procedentes de todas las áreas de distribución de Costa Rica, se observó dos patrones cariológicos principales: I o "nigrocinctus" ... -
El problema de los efectos hemorrágico y mionecrótico por mordeduras de serpiente en el continente Americano
Gutiérrez, José María; Bolaños Herrera, Róger (1980)Los efectos locales que aparecen como consecuencia de la mordedura de serpientes constituyen un problema de salud importante en las Américas. Sin embargo, la eficacia del suero antiofídico que se usa parece ser escasa, ...