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Identification of rupatadine fumarate polymorphic crystalline forms in pharmaceutical raw materials
(2018)
Polymorphism analysis of pharmaceutical raw materials is considered one of the most relevant
evaluations that should be done. As we know, different crystal forms from the same molecule have
differences in terms of their ...
Determination of the Impact Caused by Direct Compression on the Crystalline State of Rupatadine Fumarate 10 mg Tablets
(2019-11-08)
The aim of this study is to determine the impact caused by direct compression on the crystalline state of two
prototypes of Rupatadine fumarate 10 mg tablets. The tablets were manufactured through direct compression. ...
Design of Experiments for the Establishment of the Dissolution Test Conditions of Rupatadine Fumarate 10 mg tablets
(2019)
Design of Experiments (DoE) is a statistical model that aims to determine if the factors under study affect the response, and if so, it determines
the conditions under which this variable of interest can be optimized. In ...
Design of experiments assessment for the determination of moisture content in five herbal raw materials contained in tea products
(2020-02)
Research interest in natural raw materials is rapidly growing due to the high demand for natural products like herbal teas. Their quality control has a direct impact on safety and efficacy. The aim of this study was to ...
Development of immediate release Rupatadine fumarate 10 mg tablets: A Quality by Design (QbD) approach
(2019)
The main objective of this research is to develop an immediate release Rupatadine fumarate 10
mg tablets formulation by direct compression, through a Quality by Design approach in Costa
Rica.
Methods: According to a ...
Furosemide Diuretic Activity Evaluation in Female Sprague-Dawley Rats
(2019)
This research article focuses on the evaluation of the diuretic activity of Furosemide administered to a group of female Sprague Dawley rats, through the use of metabolic boxes.
Methods: A hydration volume of 5 mL/100 g ...
Combined use of DSC, TGA, XDR and NIR in the compatibility study of preformulation mixtures for the development of 10 mg tablets of Rupatadine Fumarate
(2018)
It is essential to guarantee physico-chemical compatibility between the active pharmaceutical ingredient (API) and the components that are planned to be used in the development of a pharmaceutical formulation. A successful ...