Now showing items 1-10 of 15
Combined use of DSC, TGA, XDR and NIR in the compatibility study of preformulation mixtures for the development of 10 mg tablets of Rupatadine Fumarate
It is essential to guarantee physico-chemical compatibility between the active pharmaceutical ingredient (API) and the components that are planned to be used in the development of a pharmaceutical formulation. A successful ...
Innovation in the production of a cream based on thermal waters from the surroundigs of the Arenal Volcano in Costa Rica
Introduction: Since 2009 the University of Costa Rica, through the Faculty of Pharmacy, is dedicated to promote a model of development in cosmetics in small and medium industries in rural or poorest areas of Costa Rica, ...
Evaluación de niveles plasmáticos de fenitoína en pacientes del Hospital William Allen (HWAT), Caja Costarricense de Seguro Social (CCSS)
Evaluation of phenytoin plasma levels in patients from Hospital William Allen (HWAT), Social Security Fund (CCSS)
La monitorización terapéutica de fármacos (MTF) es una herramienta válida para optimizar la farmacoterapia ,permitiendo el ajuste en la dosificación de medicamentos,tomando en cuenta las características individuales de ...
Rubus adenotrichus fruit extracts phytochemical characterization and antioxidant power evaluation for dermocosmetic formulations
There are more than 700 species of the genus Rubus, popularly known as Mora (tropical highland blackberry). In Costa Rica, the species Rubus adenotrichus has been characterized by its high content of antioxidant substances, ...
Evaluation of the critical points in the validation of 500 mg levofloxacin tablets for dissolution profile
The method was validated by ultraviolet spectrophotometry for the determination of levofloxacin 500 mg tablets using dissolution profiles to establish therapeutic equivalence. The parameters were satisfactory according ...
Determination of the Impact Caused by Direct Compression on the Crystalline State of Rupatadine Fumarate 10 mg Tablets
The aim of this study is to determine the impact caused by direct compression on the crystalline state of two prototypes of Rupatadine fumarate 10 mg tablets. The tablets were manufactured through direct compression. ...
Evaluación del poder antioxidante, propiedades fisicoquímicas y composición fitoquimica de extractos de semilla de bactris gasipaes para formulaciones dermocosméticas
Evaluation of the antioxidant power, physicochemical properties and phytochemical composition of seed extracts of bactris gasipaes for dermocosmetic formulations
Bactris gasipaes es una palmera de la cual se obtiene una fruta conocida comúnmente en Costa Rica como Pejibaye, es autóctona de América Central, muy común en la alimentación de Costa Rica, por su alto contenido de almidón ...
Physicochemical characterization of therapeutic peloids from the surroundings of Costa Rica Arenal Volcano
Costa Rica is a volcanic country, containing a variety of peloids with different physicochemical properties; also its main source of income is the tourism. Most of their abundant natural resources have not been characterized ...
Design of Experiments for the Establishment of the Dissolution Test Conditions of Rupatadine Fumarate 10 mg tablets
Design of Experiments (DoE) is a statistical model that aims to determine if the factors under study affect the response, and if so, it determines the conditions under which this variable of interest can be optimized. In ...
Identification of rupatadine fumarate polymorphic crystalline forms in pharmaceutical raw materials
Polymorphism analysis of pharmaceutical raw materials is considered one of the most relevant evaluations that should be done. As we know, different crystal forms from the same molecule have differences in terms of their ...