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Bacterial Sphingomyelinases and Phospholipases as Virulence Factors
Bacterial sphingomyelinases and phospholipases are a heterogeneous group of esterases which are usually surface associated or secreted by a wide variety of Gram-positive and Gram-negative bacteria. These enzymes hydrolyze ...
Membrane-damaging and cytotoxic sphingomyelinases and phospholipases
This chapter presents an overview of the classification, structure, and main physiopathological activities of bacterial sphingomyelinases and phospholipases, providing examples of their roles as virulence factors in several ...
Toxin B Variants from Clostridium difficile Strains VPI 10463 and NAP1/027 Share Similar Substrate Profile and Cellular Intoxication Kinetics but Use Different Host Cell Entry Factors
Clostridium difficile induces antibiotic-associated diarrhea due to the release of toxin A (TcdA) and toxin B (TcdB), the latter being its main virulence factor. The epidemic strain NAP1/027 has an increased virulence ...
New Diet Quality Index of children and adolescents in Costa Rica
Nuevo Índice de Calidad de la Dieta de niños y adolescentes en Costa Rica
Introduction: There is an increasing interest in the study of indicators of the quality of the total diet through the study of food groups of certain dietary patterns. Objective: Analyze the diet of students of Costa Rica ...
Porphyromonas spp. have an extensive host range in ill and healthy individuals and an unexpected environmental distribution: a systematic review and meta-analysis
Studies on the anaerobic bacteria Porphyromonas, mainly focused on P. gingivalis, have revealed new bacterial structures, metabolic pathways, and physiologic functionalities. Porphyromonas are mainly described as being ...