Now showing items 1-10 of 130
Reevaluación de los índices larvales para Aedes aegypti (Diptera: Culicidae) en dos localidades con historia epidemiológica de dengue, Costa Rica
Reevaluation of the larval índices for Aedes aegypti (Diptera: Culicidae) in two localities with an epidemiological histoy of dengue, Costa Rica
Introducción. En Costa Rica, el dengue es la principal enfermedad de trasmisión vectorial. Esta afecta ecosistema urbanos como La Carpio y La Gran Puntarenas, donde Aedes aegypti es altamente prevalente. Objetivo. Reevaluar ...
Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities
Clostridium difficile strains within the hypervirulent clade 2 are responsible for nosocomial outbreaks worldwide. The increased pathogenic potential of these strains has been attributed to several factors but is still ...
Molecular detection of Clostridium difficile on inert surfaces from a Costa Rican hospital during and after an outbreak
Background: Hospital transmission of Clostridium difficile is fostered by contamination of surfaces and medical equipment with spores highly resistant to disinfectants and regular cleaning procedures. Despite the outbreaks ...
A biocomputational platform for the automated construction of large-scale mathematical models of miRNA-transcription factor networks for studies on gene dosage compensation
Cancer complexity and resistance is mediated by cell-to-cell heterogeneity, which is the consequence of the enormous instability of its genetic material. It is unknown how cancer cells are able to withstand the effects ...
Global genetic diversity of Aedes aegypti
Mosquitoes, especially Aedes aegypti, are becoming important models for studying invasion biology. We characterized genetic variation at 12 microsatellite loci in 79 populations of Ae. aegypti from 30 countries in six ...
Identification of cancer chemosensitivity by ODE and GMM modeling of heterogeneous cellular response to perturbations in fluorescent sphingolipid metabolism
Cancer refers to a group of diseases in which cells display uncontrolled growth. Chemotherapy options are usually conditioned by generating resistance which is explained in part by the intrinsic heterogeneity of the ...
Biopiracy of natural products and good bioprospecting practice
Background: Biopiracy mainly focuses on the use of biological resources and/or knowledge of indigenous tribes or communities without allowing them to share the revenues generated out of economic exploitation or other ...
Zika Virus (ZIKV): A New Emerging Pathogen Transmitted by Aedes Mosquitoes (Diptera: Culicidae) in the Latin American Subcontinent
Aedes aegypti and Aedes albopictus (Diptera: Culicidae) are two species of synanthropic mosquitoes that are common in outdoor and indoor domiciliary environments in tropical countries. Their vectorial competence and ...
El virus del Zika
El virus del Zika es un arbovirus emergente. Se transmite por medio de los mosquitos del género Aedes. Fue descrito por primera vez en mosquitos y monos del bosque Zika en Uganda, en 1947; posteriormente, en seres humanos ...
Molecular Characterization of Two Major Dengue Outbreaks in Costa Rica
Dengue virus (DENV) (Flavivirus, Flaviviridae) is a reemerging arthropod-borne virus with a worldwide circulation, transmitted mainly by Aedes aegypti and Aedes albopictus mosquitoes. Since the first detection of its ...