• An acidic phospholipase A2 with antibacterial activity from Porthidium nasutum snake venom 

      Vargas Muñoz, Leidy Johana; Londoño Monsalve, Mónica; Quintana Castillo, Juan Carlos; Rua, Carolina; Segura Latorre, Cesar; Lomonte, Bruno; Núñez Rangel, Vitelbina (2012-04)
      Snake venoms are complex mixtures of proteins among which both basic and acidic phospholipases A2 (PLA2s) can be found. Basic PLA2s are usually responsible for major toxic effects induced by snake venoms, while acidic ...
    • Antiplasmodial effect of the venom of Crotalus durissus cumanensis, crotoxin complex and Crotoxin B 

      Quintana, Juan Carlos; Chacón, A. M.; Vargas Muñoz, Leidy Johana; Segura Latorre, Cesar; Gutiérrez, José María; Alarcón, Juan Carlos (2012-11)
      The antiplasmodial activity of phospholipases A2 (PLA2) isolated from different animals has been studied. We explored the in vitro anti Plasmodium falciparum effect of a fraction containing crotoxin, Crotoxin B and whole ...
    • Comparative study of the efficacy and safety of two polyvalent, caprylic acid fractionated [IgG and F(ab0)2] antivenoms, in Bothrops asper bites in Colombia 

      Otero Patiño, Rafael; Segura Ruiz, Álvaro; Pereañez, Jaime Andrés; Herrera Vega, María; Angulo Ugalde, Yamileth; León Montero, Guillermo; Gutiérrez, José María; Barona, Jacqueline; Estrada, Sebastián; Quintana, Juan Carlos; Vargas Muñoz, Leidy Johana; Gómez, Juan Pablo; Díaz, Abel; Suárez, Ana María; Fernández, Jorge; Ramírez, Patricia; Fabra, Patricia E.; Perea, Monica; Fernández, Diego; Arroyo, Yobana; Betancur, Dalila; Pupo, Lady; Córdoba, Elkin; Ramírez, Eugenio; Arrieta, Ana Berta; Rivero, Alcides; Mosquera, Diana Carolina; Conrado, Nectty Lorena; Ortiz, Rosina (2012-02)
      The efficacy and safety of two polyvalent horse-derived antivenoms in Bothrops asper envenomings were tested in a randomized, double-blind, clinical trial performed in Colombia. Both antivenoms were manufactured from the ...