Listar Microbiología por autor "Ramírez Vargas, Gabriel"
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A Clostridium difficile Lineage Endemic to Costa Rican Hospitals Is Multidrug Resistant by Acquisition of Chromosomal Mutations and Novel Mobile Genetic Elements
Ramírez Vargas, Gabriel; Quesada Gómez, Carlos; Acuña Amador, Luis Alberto; López Ureña, Diana; Murillo Corrales, Tatiana; Gamboa Coronado, María del Mar; Chaves Olarte, Esteban; Thomson, Nicholas R.; Rodríguez Cavallini, Evelyn; Rodríguez Sánchez, César (2017-01)The antimicrobial resistance (AMR) rates and levels recorded for Clostridium difficile are on the rise. This study reports the nature, levels, diversity, and genomic context of the antimicrobial resistance of human C. ... -
Novel Clade C-I Clostridium difficile strains escape diagnostic tests, differ in pathogenicity potential and carry toxins on extrachromosomal elements
Ramírez Vargas, Gabriel; López Ureña, Diana; Badilla Lobo, Adriana; Orozco Aguilar, Josué; Murillo Corrales, Tatiana; Rojas, Priscilla; Riedel, Thomas; Overmann, Jörg; González, Gabriel; Chaves Olarte, Esteban; Quesada Gómez, Carlos; Rodríguez Sánchez, César (2018)The population structure of Clostridium difficile currently comprises eight major genomic clades. For the highly divergent C-I clade, only two toxigenic strains have been reported, which lack the tcdA and tcdC genes and ... -
The Novel Phages phiCD5763 and phiCD2955 Represent Two Groups of Big Plasmidial Siphoviridae Phages of Clostridium difficile
Ramírez Vargas, Gabriel; Goh, Shan; Rodríguez Sánchez, César (2018-01)Until recently, Clostridium difficile phages were limited to Myoviruses and Siphoviruses of medium genome length (32–57 kb). Here we report the finding of phiCD5763, a Siphovirus with a large extrachromosomal circular ... -
Two Groups of Cocirculating, Epidemic Clostridiodes difficile Strains Microdiversify through Different Mechanisms
Murillo Corrales, Tatiana; Ramírez Vargas, Gabriel; Riedel, Thomas; Overmann, Jörg; Andersen, Joakim M; Guzmán Verri, Caterina; Chaves Olarte, Esteban; Rodríguez Sánchez, César (2018-03)Clostridiodes difficile strains from the NAPCR1/ST54 and NAP1/ST01 types have caused outbreaks despite of their notable differences in genome diversity. By comparing whole genome sequences of 32 NAPCR1/ST54 isolates and ...