Browsing Microbiología by Author "Olamendi Portugal, Timoteo"
Now showing items 1-3 of 3
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Cleavage of the NH2-Terminal Octapeptide of Bothrops asper Myotoxic Lysine-49 Phospholipase A2 Reduces Its Membrane-Destabilizing Effect
Díaz Oreiro, Cecilia; Alape Girón, Alberto; Lomonte, Bruno; Olamendi Portugal, Timoteo; Gutiérrez, José María (1994-08)Bothrops asper myotoxin II was cleaved with cyanogen bromide to determine the role of NH2-terminal amino acid residues in its ability to destabilize negatively charged liposomes and to induce myonecrosis. After treatment, ... -
Isolation and characterization of myotoxin II from Atropoides (Bothrops) nummifer snake venom, a new Lys49 phospholipase A2 homologu
Angulo Ugalde, Yamileth; Olamendi Portugal, Timoteo; Possani, Lourival D.; Lomonte, Bruno (2000)Myotoxic phospholipases A2 of class II are commonly found in the venoms of crotalid snakes. As an approach to understanding their structure±activity relationship, diverse natural variants have been characterized ... -
Structural characterization and phylogenetic relationships of myotoxin II from Atropoides (Bothrops) nummifer snake venom, a Lys49 phospholipase A2 homologue
Angulo Ugalde, Yamileth; Olamendi Portugal, Timoteo; Alape Girón, Alberto; Possani, Lourival D.; Lomonte, Bruno (2002)In order to analyze its structure–function relationships, the complete amino acid sequence of myotoxin II from Atropoides (Bothrops) nummifer from Costa Rica was determined. This toxin is a Lys49-type phospholipase A2 ...