Listar Microbiología por autor "Karatt Vellatt, Aneesh"

Mostrando ítems 1-4 de 4

    • Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper 

      Sørensen, Christoffer V.; Fernández, Julián; Adams, Anna Christina; Wildenauer, Helen H. K.; Schoffelen, Sanne; Ledsgaard, Line; Pucca, Manuela Berto; Fiebig, Michael; Cerni, Felipe A.; Tulika, Tulika; Voldborg, Bjørn; Karatt Vellatt, Aneesh; Morth, J. Preben; Ljungars, Anne; Grav, Lise M.; Lomonte, Bruno; Laustsen, Andreas Hougaard (2024)
      Improved therapies are needed against snakebite envenoming, which kills and permanently disables thousands of people each year. Recently developed neutralizing monoclonal antibodies against several snake toxins have ...

    • Discovery and optimization of a broadly-neutralizing human antibody against long-chain α-neurotoxins from snakes 

      Ledsgaard, Line; Wade, Jack; Jenkins, Timothy P.; Boddum, Kim; Oganesyan, Irina; Harrison, Julian A.; Villar, Pedro; Leah, Rachael A.; Zenobi, Renato; Schoffelen, Sanne; Voldborg, Bjørn; Ljungars, Anne; McCafferty, John; Lomonte, Bruno; Gutiérrez, José María; Laustsen, Andreas Hougaard; Karatt Vellatt, Aneesh (2023-02-08)
      Snakebite envenoming continues to claim many lives across the globe, necessitating the development of improved therapies. To this end, broadly-neutralizing human monoclonal antibodies may possess advantages over current ...

    • In vitro discovery of a human monoclonal antibody that neutralizes lethality of cobra snake venom. 

      Ledsgaard, Line; Laustsen, Andreas Hougaard; Pus, Urska; Wade, Juli S.; Villar, Pedro; Boddum, Kim; Slanvy, Peter; Masters, Edward W.; Arias Oviedo, Ana Silvia; Oscoz, Saioa; Griffiths, Daniel T.; Luther, Alice M.; Linholm, Majken; Leah, Rachael A.; Møller, Marie Sofie; Ali, Hanif; McCafferty, John; Lomonte, Bruno; Gutiérrez, José María; Karatt Vellatt, Aneesh (2022)
      The monocled cobra (Naja kaouthia) is among the most feared snakes in Southeast Asia due to its toxicity, which is predominantly derived from long-chain α-neurotoxins. The only specific treatment for snakebite envenoming ...

    • In vivo neutralization of the dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG monoclonal antibodies 

      Laustsen, Andreas Hougaard; Karatt Vellatt, Aneesh; Masters, Edward W.; Arias Oviedo, Ana Silvia; Pus, Urska; Knudsen, Cecilie; Oscoz, Saioa; Slavny, Peter; Griffiths, Daniel T.; Luther, Alice M.; Leah, Rachael A.; Lindholm, Majken; Lomonte, Bruno; Gutiérrez, José María; McCafferty, John (2018)
      The black mamba (Dendroaspis polylepis) is one of the most feared snake species of the African savanna. It has a potent, fast-acting neurotoxic venom comprised of dendrotoxins and α-neurotoxins associated with high ...