Now showing items 1-5 of 5

    • Brucella abortus Induces the Premature Death of Human Neutrophils through the Action of Its Lipopolysaccharide 

      Barquero Calvo, Elías; Mora Cartín, Ricardo; Arce Gorvel, Vilma; de Diego, Juana L.; Chacón Díaz, Carlos; Chaves Olarte, Esteban; Guzmán Verri, Caterina; Buret, Andre G.; Gorvel, Jean Pierre; Moreno Robles, Edgardo (2015-05-06)
      Most bacterial infections induce the activation of polymorphonuclear neutrophils (PMNs), enhance their microbicidal function, and promote the survival of these leukocytes for protracted periods of time. Brucella abortus ...
    • Brucella abortus Strain 2308 Wisconsin Genome: Importance of the Definition of Reference Strains 

      Suárez Esquivel, Marcela; Ruiz Villalobos, Nazareth; Castillo Zeledón, Amanda; Jiménez Rojas, César; Martin Roop II, Roy; Comerci, Diego J.; Barquero Calvo, Elías; Chacón Díaz, Carlos; Caswell, Clayton C.; Baker, Kate S.; Chaves Olarte, Esteban; Thomson, Nicholas R.; Moreno Robles, Edgardo; Letesson, Jean J.; De Bolle, Xavier; Guzmán Verri, Caterina (2016-09-29)
      Brucellosis is a bacterial infectious disease affecting a wide range of mammals and a neglected zoonosis caused by species of the genetically homogenous genus Brucella. As in most studies on bacterial diseases, research ...
    • Brucella canis Is an Intracellular Pathogen That Induces a Lower Proinflammatory Response than Smooth Zoonotic Counterparts 

      Chacón Díaz, Carlos; Altamirano Silva, Pamela; González Espinoza, Gabriela; Medina, María Concepción; Alfaro Alarcón, Alejandro; Bouza Mora, Laura; Jiménez Rojas, César; Wong Araya, Melissa; Barquero Calvo, Elías; Rojas Campos, Norman; Guzmán Verri, Caterina; Moreno Robles, Edgardo; Chaves Olarte, Esteban (2015-11-10)
      Canine brucellosis caused by Brucella canis is a disease of dogs and a zoonotic risk. B. canis harbors most of the virulence determinants defined for the genus, but its pathogenic strategy remains unclear since it has not ...
    • Depletion of complement enhances the clearance of Brucella abortus in mice 

      González Espinoza, Gabriela; Barquero Calvo, Elías; Lizano González, Esteban; Alfaro Alarcón, Alejandro; Arias Gómez, Berny; Chaves Olarte, Esteban; Lomonte, Bruno; Moreno, Edgardo; Chacón Díaz, Carlos (2018)
      Brucellosis is a bacterial disease of animals and humans. Brucella abortus barely activates the innate immune system at the onset of infection, and this bacterium is resistant to the microbicidal action of complement. ...
    • N-Formyl-Perosamine Surface Homopolysaccharides Hinder the Recognition of Brucella abortus by Mouse Neutrophils 

      Mora Cartín, Ricardo; Chacón Díaz, Carlos; Gutiérrez Jiménez, Cristina; Gurdián Murillo, Stephany; Lomonte, Bruno; Chaves Olarte, Esteban; Barquero Calvo, Elías; Moreno Robles, Edgardo (2016-06)
      Brucella abortus is an intracellular pathogen of monocytes, macrophages, dendritic cells, and placental trophoblasts. This bacterium causes a chronic disease in bovines and in humans. In these hosts, the bacterium also ...