Listar Microbiología por título
Mostrando ítems 696-715 de 1168
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Localization of Myotoxin I and Myotoxin II from the venom of Bothrops asper in a murine model
(2021)Phospholipases A2 (PLA2s) and PLA2-like proteins are significant components of snake venoms. Some of these proteins act as potent toxins causing muscle necrosis, which may lead to amputation in severe envenomings. Fundamental ... -
Longitud larval de Hemilucilia segmentaria (Diptera: Calliphoridae) como indicador del intervalo post-mortem en Costa Rica
(2003-12-31)La longitud larval de Hemilucilia segmentar/a (Diptera: Calliphorldae) fue evaluada como un Indicador del intervalo post-mortem (IPM) en un modelo experimental. Se realizaron observaciones por triplicado en cadáveres de ... -
Low pH formulation of whole IgG antivenom: Impact on quality, safety, neutralizing potency and viral inactivation
(2012-03)Low pH treatment improves the tolerance to intravenous infusion, the stability, and the viral safety of various therapeutic immunoglobulins G preparations, but has never been evaluated for horse plasma-derived antivenoms. ... -
Low-cost internal controls for detection of Giardia cysts in water samples
(2019-08)Giardia cysts stained with hot carbolfuchsin were used as internal controls in a concentration method for surface water samples. The morphological integrity of stained cysts and the stain's stability and intensity were ... -
Lys-49 phospholipases A2 as active enzymes for beta-arachidonoyl phospholipid bilayer membranes
(1997)Phospholipases A2 containing Lys-49 have been reported to be extremely weak or inactive as enzyme. We have recently shown that basic proteins I and II (BP-I and BP-II), Lys- 49-PLA2s isolated from the venom of Trimeresurus ... -
Lys49 myotoxins, secreted phospholipase A2-like proteins of viperid venoms: a comprehensive review
(2023)Muscle necrosis is a potential clinical complication of snakebite envenomings, which in severe cases can lead to functional or physical sequelae such as disability or amputation. Snake venom proteins with the ability to ... -
Malassezia spp: una actualización del estado del conocimiento
(2021-07)Este manuscrito corresponde a una actualización del estado del conocimiento sobre el género Malassezia, contemplando sus aspectos taxonómicos, etiología, ecología, relaciones inmunológicas y manifestaciones clínicas ... -
Mapping the risk of Aedes aegypti larval habitats using tree cover in Puntarenas, Costa Rica
(2010-08)Tree cover and other characteristics of urban structure have been associated in urban environments with abundance and productivity of Aedes aegypti and other mosquito larval habitats. Tree cover can conceal containers, ... -
Mecanismo de açao dos venenos de cobras corais
(2016)Os venenos apresentam um importante papel fisiológico para as serpentes: são os fatores responsáveis pela subjugação das presas, iniciam e auxiliam sua digestão e constituem um mecanismo de defesa contra predadores/agressores, ... -
Mechanisms of low susceptibility to the disinfectant benzalkonium chloride in a multidrug-resistant environmental isolate of Aeromonas hydrophila
(2023)Excessive discharge of quaternary ammonium disinfectants such as benzalkonium chloride (BAC) into aquatic systems can trigger several physiological responses in environmental microorganisms. In this study, we isolated a ... -
Medicamentos que potencialmente pueden afectar la condición de salud bucodental de personas adultas mayores de Los Guido de Desamparados en Costa Rica. Revista Internacional de Salud, Bienestar y Sociedad.
(2023-08-03)Este trabajo se enmarca en el macroproyecto de investigación del Instituto de Investigaciones en Salud de la Universidad de Costa Rica que estudia la situación de la persona adulta mayor en una comunidad urbano marginal, ... -
Medicinal plants with inhibitory properties against snake venoms
(2005)Envenomations due to snake bites are commonly treated by parenteral administration of horse or sheep-derived polyclonal antivenoms aimed at the neutralization of toxins. However, despite the widespread success of this ... -
Mejora de la Gestión del Sistema Documental en la División de Diagnóstico Molecular del Laboratorio Clínico del Hospital México
(2023)Este trabajo tiene como objetivo la mejora del sistema de gestión documental de la División de Diagnóstico Molecular del Hospital México. Es relevante debido a la necesidad de estandarización y ejecución eficaz de las ... -
Membrane cholesterol modulates the cytolytic mechanism of myotoxin II, a Lys49 phospholipase A2 homologue from the venom of Bothrops asper
(2011-04-19)Lys49 phospholipase A2 (PLA2) homologues present in crotalid snake venoms lack enzymatic activity, yet they induce skeletal muscle necrosis by a membrane permeabilizing mechanism whose details are only partially understood. ... -
Membrane independent activation of fibroblast proMMP-2 by snake venom: novel roles for venom proteinases
(2004-12-01)ProMMP-2 activation by Bothrops asper venom was investigated in mouse gastrocnemius muscle, mammalian cell culture and a cell-free system. Zymography revealed an increment of latent and activated forms of MMP-2 in muscle ... -
Membrane-damaging and cytotoxic sphingomyelinases and phospholipases
(2015-06-05)This chapter presents an overview of the classification, structure, and main physiopathological activities of bacterial sphingomyelinases and phospholipases, providing examples of their roles as virulence factors in several ... -
Metagenomic pipeline for identifying co-infections among distinct SARS-CoV-2 variants of concern: Study cases from Alpha to Omicron
(2022)Concomitant infection or co-infection with distinct SARS-CoV-2 genotypes have been reported as part of the epidemiological surveillance of the COVID-19 pandemic. In the context of the spread of more transmissible variants ... -
Metaloproteinasas dependientes de Zinc: Protagonistas centrales en la Fisiopatología de Envenenamientos por Serpientes de la familia Viperidae
(2016)Se presenta y discute el papel que juegan las metaloproteinasas de los venenos de serpientes (SVMPs) de la familia Viperidae en la fisiopatología de los envenenamientos inducidos por mordeduras de estos reptiles. Se hace ... -
Methyltestosterone alters sex determination in the American alligator (Alligator mississippiensis)
(2016-07-09)Effects of xenobiotics can be organizational, permanently affecting anatomy during embryonic development, and/or activational, influencing transitory actions during adulthood. The organizational influence of endocrine-disrupting ... -
Mevalonate pathway as a novel target for the treatment of metastatic gastric cancer
(2020-10)Gastric mucosa tumors may present as two distinct major entities: Diffuse and intestinal subtypes. There is no standard treatment for advanced or metastatic gastric cancer. The mevalonate pathway and cholesterol homeostasis ...