Listar Microbiología por título
Mostrando ítems 678-697 de 1169
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Isolation of an acidic phospholipase A2 from the venom of the snake Bothrops asper of Costa Rica: Biochemical and toxicological characterization
(2010-03)Phospholipases A2 (PLA2) are major components of snake venoms, exerting a variety of relevant toxic actions such as neurotoxicity and myotoxicity, among others. Since the majority of toxic PLA2s are basic proteins, acidic ... -
Isolation of basic myotoxins from Bothrops Moojeni and Bothrops Atrox snake venoms
(1990)Three myotoxins, one from the venom of Bothrops atrox and two from the venom of B. moojeni, were isolated by ion-exchange chromatography on CM-Sephadex C-25. The three toxins are basic proteins with an estimated mol. wt ... -
Isolation of two basic phospholipases A2 from Bothrops diporus snake venom: comparative characterization and synergism between Asp49 and Lys49 variants
(2019)Bothrops diporus, previously considered a subspecies of the B. neuwiedi complex, is a medically relevant viperid in Northeastern Argentina. The venom of this species causes local tissue damage characterized by ... -
Isolation, characterization and molecular cloning of AnMIP, a new α-type phospholipase A2 myotoxin inhibitor from the plasma of the snake Atropoides nummifer (Viperidae: Crotalinae)
(2007)A new phospholipase A2 (PLA2)-inhibitory protein was isolated from the plasma of Atropoides nummifer, a crotaline snake from Central America. This inhibitor was named AnMIP, given its ability to neutralize the activity ... -
Índices bibliométricos y revistas de ‘corriente central’: implicaciones para el desarrollo de las ciencias naturales en Costa Rica
(2015)Dada esta amplia variación en la calidad de las publicaciones en ciencias naturales, es esencial para la comunidad científica tener una perspectiva clara de dicha heterogeneidad y de sus implicaciones ... -
Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases
(2011-08-24)Hemorrhage is one of the most significant effects in envenomings induced by viperid snakebites. Damage to the microvasculature, induced by snake venom metalloproteinases (SVMPs), is the main event responsible for this ... -
La investigación en la Universidad de Costa Rica: situación actual y perspectivas
(Editorial de la Universidad de Costa Rica, 2005)En este trabajo se analizan algunas de las características actuales de la actividad de investigación científico-tecnológica en la Universidad de Costa Rica (UCR) y se plantean medidas tendientes a consolidar esta importante ... -
Lachesis stenophrys venom reduces the equine antibody response towards Bothrops asper venom used as co-immunogen in the production of polyspecific snake antivenom
(2015-09-01)The anti-bothropic activity of an antivenom prepared from the plasma of horses immunized with Bothrops asper venom (anti-B antivenom) was compared with a similar formulation produced from the plasma of horses immunized ... -
Lemnitoxin, the major component of Micrurus lemniscatus coral snake venom, is a myotoxic and pro-inflammatory phospholipase A2
(2016-08-26)The venom of Micrurus lemniscatus, a coral snake of wide geographical distribution in South America, was fractionated by reverse-phase HPLC and the fractions screened for phospholipase A2 (PLA2) activity. The major component ... -
Lettuce for Human Consumption Collected in Costa Rica Contains Complex Communities of Culturable Oxytetracycline- and Gentamicin-Resistant Bacteria
(2006-09)The present widespread use of antimicrobials in crop farming is based upon their successful application in human medicine. However, recent evidence suggests that the massive anthropogenic release of antimicrobials into ... -
Leucemia Mieloide Crónica Juvenil. A propósito de un caso
(2019-05-01)La leucemia Mieloide Crónica (LMC) es una neoplasia mieloproliferativa crónica, caracterizada por un gen de fusión t(9,22). El curso normal de la enfermedad consta de 3 fases: crónica, acelerada y blástica. En su gran ... -
Lineamientos teórico-prácticos de la investigación "La educación como promotora de salud integral de la niñez y la adolescencia en y desde los centros educativos costarricenses"
(2012)El propósito de este artículo es presentar los fundamentos teórico-prácticos de la investigación acción, que guían la primera etapa diagnóstica del proyecto de investigación: "La educación como promotora de salud integral ... -
Local and systemic pathophysiological alterations induced by a serine proteinase from the venom of the snake Bothrops jararacussu
(2007-06-01)The local and systemic pathophysiological alterations induced by BjussuSP-I, a thrombin-like serine proteinase from the venom of the snake Bothrops jararacussu, were assessed in mice. BjussuSP-I induced a mild edema but ... -
Local effects induced by coral snake venoms: Evidence of myonecrosis after experimental inoculations of venoms from five species
(1983)The local effects induced by intramuscular inoculations of venons from six species of coral snakes were studied in mice. Venoms of Micrurus nlgrocinctus nigrocinctus, M. n . moquitensis, M. alleni, M. frontalis, M. aarinkauda ... -
Local tissue damage induced by BaP1, a metalloproteinase isolated from Bothrops asper (Terciopelo) snake venom
(1995-12)The pathogenesis of hemorrhage and other local effects induced by the metalloproteinase BaP1, isolated from Bothrops asper venom, was investigated using various in vivo and in vitro models. Upon intramuscular injection in ... -
Local tissue damage induced by Bothrops snake venoms - A review
(1989-12)This review focuses on the local effects induced by Bothrops venoms. These envenomation are characterized by myonecrosis, hemorrhage and edema which develop rapidly after venom inoculation. Myonecrosis is caused (a) directly, ... -
Localization of Myotoxin I and Myotoxin II from the venom of Bothrops asper in a murine model
(2021)Phospholipases A2 (PLA2s) and PLA2-like proteins are significant components of snake venoms. Some of these proteins act as potent toxins causing muscle necrosis, which may lead to amputation in severe envenomings. Fundamental ... -
Longitud larval de Hemilucilia segmentaria (Diptera: Calliphoridae) como indicador del intervalo post-mortem en Costa Rica
(2003-12-31)La longitud larval de Hemilucilia segmentar/a (Diptera: Calliphorldae) fue evaluada como un Indicador del intervalo post-mortem (IPM) en un modelo experimental. Se realizaron observaciones por triplicado en cadáveres de ...